The use of ECMO in pediatric granulomatosis with polyangiitis

BACKGROUND: Granulomatosis with polyangiitis (GPA) vasculitis with pulmonary-renal syndrome rarely presents in children and is associated with high mortality rates. CASE PRESENTATION: We present the case of a 13-year-old male with newly diagnosed GPA vasculitis, treated with extracorporeal membrane...

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Detalles Bibliográficos
Autores principales: Finkel, Rachel, Honig, Jesse, Chao, Chun P., Rescoe, Erin, Solomon, Sonia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9092879/
https://www.ncbi.nlm.nih.gov/pubmed/35538584
http://dx.doi.org/10.1186/s12969-022-00693-8
Descripción
Sumario:BACKGROUND: Granulomatosis with polyangiitis (GPA) vasculitis with pulmonary-renal syndrome rarely presents in children and is associated with high mortality rates. CASE PRESENTATION: We present the case of a 13-year-old male with newly diagnosed GPA vasculitis, treated with extracorporeal membrane oxygenation, continuous renal replacement therapy, plasmapheresis, rituximab, cyclophosphamide, and corticosteroids. CONCLUSION: This case presentation demonstrates that ECMO can be used as a life supporting therapy in pediatric patients with pulmonary hemorrhage from ANCA vasculitis in conjunction with other therapies.

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