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The use of ECMO in pediatric granulomatosis with polyangiitis

BACKGROUND: Granulomatosis with polyangiitis (GPA) vasculitis with pulmonary-renal syndrome rarely presents in children and is associated with high mortality rates. CASE PRESENTATION: We present the case of a 13-year-old male with newly diagnosed GPA vasculitis, treated with extracorporeal membrane...

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Autores principales: Finkel, Rachel, Honig, Jesse, Chao, Chun P., Rescoe, Erin, Solomon, Sonia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9092879/
https://www.ncbi.nlm.nih.gov/pubmed/35538584
http://dx.doi.org/10.1186/s12969-022-00693-8
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author Finkel, Rachel
Honig, Jesse
Chao, Chun P.
Rescoe, Erin
Solomon, Sonia
author_facet Finkel, Rachel
Honig, Jesse
Chao, Chun P.
Rescoe, Erin
Solomon, Sonia
author_sort Finkel, Rachel
collection PubMed
description BACKGROUND: Granulomatosis with polyangiitis (GPA) vasculitis with pulmonary-renal syndrome rarely presents in children and is associated with high mortality rates. CASE PRESENTATION: We present the case of a 13-year-old male with newly diagnosed GPA vasculitis, treated with extracorporeal membrane oxygenation, continuous renal replacement therapy, plasmapheresis, rituximab, cyclophosphamide, and corticosteroids. CONCLUSION: This case presentation demonstrates that ECMO can be used as a life supporting therapy in pediatric patients with pulmonary hemorrhage from ANCA vasculitis in conjunction with other therapies.
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spelling pubmed-90928792022-05-12 The use of ECMO in pediatric granulomatosis with polyangiitis Finkel, Rachel Honig, Jesse Chao, Chun P. Rescoe, Erin Solomon, Sonia Pediatr Rheumatol Online J Case Report BACKGROUND: Granulomatosis with polyangiitis (GPA) vasculitis with pulmonary-renal syndrome rarely presents in children and is associated with high mortality rates. CASE PRESENTATION: We present the case of a 13-year-old male with newly diagnosed GPA vasculitis, treated with extracorporeal membrane oxygenation, continuous renal replacement therapy, plasmapheresis, rituximab, cyclophosphamide, and corticosteroids. CONCLUSION: This case presentation demonstrates that ECMO can be used as a life supporting therapy in pediatric patients with pulmonary hemorrhage from ANCA vasculitis in conjunction with other therapies. BioMed Central 2022-05-10 /pmc/articles/PMC9092879/ /pubmed/35538584 http://dx.doi.org/10.1186/s12969-022-00693-8 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Case Report
Finkel, Rachel
Honig, Jesse
Chao, Chun P.
Rescoe, Erin
Solomon, Sonia
The use of ECMO in pediatric granulomatosis with polyangiitis
title The use of ECMO in pediatric granulomatosis with polyangiitis
title_full The use of ECMO in pediatric granulomatosis with polyangiitis
title_fullStr The use of ECMO in pediatric granulomatosis with polyangiitis
title_full_unstemmed The use of ECMO in pediatric granulomatosis with polyangiitis
title_short The use of ECMO in pediatric granulomatosis with polyangiitis
title_sort use of ecmo in pediatric granulomatosis with polyangiitis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9092879/
https://www.ncbi.nlm.nih.gov/pubmed/35538584
http://dx.doi.org/10.1186/s12969-022-00693-8
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