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Solvent-free amide bond formation using a variety of methoxysilanes as coupling agent

A solvent-free procedure for the formation of amides without exclusion of air and moisture is described. Using tetramethoxysilane 1, hexamethoxydisilane 2 and dodecamethoxy-neopentasilane 3 as coupling agent carboxylic acids and amines are reacted to form amides in good to excellent yields. The form...

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Detalles Bibliográficos
Autores principales: Lainer, Thomas, Czerny, Frank, Haas, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9092949/
https://www.ncbi.nlm.nih.gov/pubmed/35441639
http://dx.doi.org/10.1039/d2ob00589a

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