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Spacer Domain in Hepatitis B Virus Polymerase: Plugging a Hole or Performing a Role?
Hepatitis B virus (HBV) polymerase is divided into terminal protein, spacer, reverse transcriptase, and RNase domains. Spacer has previously been considered dispensable, merely acting as a tether between other domains or providing plasticity to accommodate deletions and mutations. We explore evidenc...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Microbiology
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9093120/ https://www.ncbi.nlm.nih.gov/pubmed/35412348 http://dx.doi.org/10.1128/jvi.00051-22 |