Differential effects of cyclo-oxygenase 1 and 2 inhibition on angiogenesis inhibitor-induced hypertension and kidney damage

Vascular endothelial growth factor antagonism with angiogenesis inhibitors in cancer patients induces a ‘preeclampsia-like’ syndrome including hypertension, proteinuria and elevated endothelin (ET)-1. Cyclo-oxygenase (COX) inhibition with aspirin is known to prevent the onset of preeclampsia in high...

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Detalles Bibliográficos
Autores principales: Mirabito Colafella, Katrina M., van Dorst, Daan C.H., Neuman, Rugina I., Doorn, Leni van, Neves, Karla Bianca, Montezano, Augusto C., Garrelds, Ingrid M., van Veghel, Richard, de Vries, René, Uijl, Estrellita, Clahsen-van Groningen, Marian C., Baelde, Hans J., van den Meiracker, Anton H., Touyz, Rhian M., Visser, Willy, Danser, A.H. Jan, Versmissen, Jorie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2022
Materias:
Cardiovascular System & Vascular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9093150/
https://www.ncbi.nlm.nih.gov/pubmed/35441670
http://dx.doi.org/10.1042/CS20220182

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9093150/
https://www.ncbi.nlm.nih.gov/pubmed/35441670
http://dx.doi.org/10.1042/CS20220182

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