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A photoresponsive antibody–siRNA conjugate for activatable immunogene therapy of cancer

Tumor-targeted delivery of small-interfering RNAs (siRNAs) for cancer therapy still remains a challenging task. While antibody–siRNA conjugates (ARCs) provide an alternative way to address this challenge, the uncontrollable siRNA release potentially leads to undesirable off-tumor side effects, limit...

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Detalles Bibliográficos
Autores principales: Wang, Xingxing, Xiao, Xiao, Feng, Yi, Li, Jinbo, Zhang, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9093185/
https://www.ncbi.nlm.nih.gov/pubmed/35655569
http://dx.doi.org/10.1039/d2sc01672a