Clinical perspectives on vagus nerve stimulation: present and future

The vagus nerve, the great wanderer, is involved in numerous processes throughout the body and vagus nerve stimulation (VNS) has the potential to modulate many of these functions. This wide-reaching capability has generated much interest across a range of disciplines resulting in several clinical tr...

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Detalles Bibliográficos
Autores principales: Goggins, Eibhlin, Mitani, Shuhei, Tanaka, Shinji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2022
Materias:
Optogenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9093220/
https://www.ncbi.nlm.nih.gov/pubmed/35536161
http://dx.doi.org/10.1042/CS20210507
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author Goggins, Eibhlin
Mitani, Shuhei
Tanaka, Shinji
author_facet Goggins, Eibhlin
Mitani, Shuhei
Tanaka, Shinji
author_sort Goggins, Eibhlin
collection PubMed
description The vagus nerve, the great wanderer, is involved in numerous processes throughout the body and vagus nerve stimulation (VNS) has the potential to modulate many of these functions. This wide-reaching capability has generated much interest across a range of disciplines resulting in several clinical trials and studies into the mechanistic basis of VNS. This review discusses current preclinical and clinical evidence supporting the efficacy of VNS in different diseases and highlights recent advancements. Studies that provide insights into the mechanism of VNS are considered.
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spelling pubmed-90932202022-05-19 Clinical perspectives on vagus nerve stimulation: present and future Goggins, Eibhlin Mitani, Shuhei Tanaka, Shinji Clin Sci (Lond) Optogenetics The vagus nerve, the great wanderer, is involved in numerous processes throughout the body and vagus nerve stimulation (VNS) has the potential to modulate many of these functions. This wide-reaching capability has generated much interest across a range of disciplines resulting in several clinical trials and studies into the mechanistic basis of VNS. This review discusses current preclinical and clinical evidence supporting the efficacy of VNS in different diseases and highlights recent advancements. Studies that provide insights into the mechanism of VNS are considered. Portland Press Ltd. 2022-05 2022-05-10 /pmc/articles/PMC9093220/ /pubmed/35536161 http://dx.doi.org/10.1042/CS20210507 Text en © 2022 The Author(s). https://creativecommons.org/licenses/by/4.0/This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) (https://creativecommons.org/licenses/by/4.0/) . Open access for this article was enabled by the participation of University of Tokyo in an all-inclusive Read & Publish agreement with Portland Press and the Biochemical Society.
spellingShingle Optogenetics
Goggins, Eibhlin
Mitani, Shuhei
Tanaka, Shinji
Clinical perspectives on vagus nerve stimulation: present and future
title Clinical perspectives on vagus nerve stimulation: present and future
title_full Clinical perspectives on vagus nerve stimulation: present and future
title_fullStr Clinical perspectives on vagus nerve stimulation: present and future
title_full_unstemmed Clinical perspectives on vagus nerve stimulation: present and future
title_short Clinical perspectives on vagus nerve stimulation: present and future
title_sort clinical perspectives on vagus nerve stimulation: present and future
topic Optogenetics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9093220/
https://www.ncbi.nlm.nih.gov/pubmed/35536161
http://dx.doi.org/10.1042/CS20210507
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