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Multisystem Inflammatory Syndrome in Children (MIS-C) With Hematological Manifestations: A Case Report

Multisystem inflammatory syndrome in children (MIS-C) is a new emerging severe form of coronavirus disease 2019 (COVID-19) that recently has been recognized in April 2020 in the United States and the United Kingdom. MIS-C is an uncommon condition that mainly affects children who previously had a COV...

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Detalles Bibliográficos
Autores principales: Alrefaey, Yazeid, Alamoudi, Ahmad, Johar, Reshale, Albar, Rawia F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9093252/
https://www.ncbi.nlm.nih.gov/pubmed/35573511
http://dx.doi.org/10.7759/cureus.24035
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author Alrefaey, Yazeid
Alamoudi, Ahmad
Johar, Reshale
Albar, Rawia F
author_facet Alrefaey, Yazeid
Alamoudi, Ahmad
Johar, Reshale
Albar, Rawia F
author_sort Alrefaey, Yazeid
collection PubMed
description Multisystem inflammatory syndrome in children (MIS-C) is a new emerging severe form of coronavirus disease 2019 (COVID-19) that recently has been recognized in April 2020 in the United States and the United Kingdom. MIS-C is an uncommon condition that mainly affects children who previously had a COVID-19 infection, and it can have serious outcomes if left untreated properly. The full clinical spectrum of this disease is yet not fully determined or understood. Here, we report a case of a 12-year-old girl, previously medically free, who presented to the emergency room complaining of shortness of breath and dizziness for two days. The patient was confirmed to have a COVID-19 infection in the workup. Laboratory studies showed elevated inflammatory markers, leukopenia, and elevated liver enzymes. Upon admission, the patient developed a persistent fever with a spike of 40ºC, not resolved with antibiotics or anti-inflammatory drugs. This was managed with intravenous immunoglobulin (IVIG) followed by steroids but did not show dramatic change initially. The patient eventually improved with management and was discharged.
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spelling pubmed-90932522022-05-14 Multisystem Inflammatory Syndrome in Children (MIS-C) With Hematological Manifestations: A Case Report Alrefaey, Yazeid Alamoudi, Ahmad Johar, Reshale Albar, Rawia F Cureus Emergency Medicine Multisystem inflammatory syndrome in children (MIS-C) is a new emerging severe form of coronavirus disease 2019 (COVID-19) that recently has been recognized in April 2020 in the United States and the United Kingdom. MIS-C is an uncommon condition that mainly affects children who previously had a COVID-19 infection, and it can have serious outcomes if left untreated properly. The full clinical spectrum of this disease is yet not fully determined or understood. Here, we report a case of a 12-year-old girl, previously medically free, who presented to the emergency room complaining of shortness of breath and dizziness for two days. The patient was confirmed to have a COVID-19 infection in the workup. Laboratory studies showed elevated inflammatory markers, leukopenia, and elevated liver enzymes. Upon admission, the patient developed a persistent fever with a spike of 40ºC, not resolved with antibiotics or anti-inflammatory drugs. This was managed with intravenous immunoglobulin (IVIG) followed by steroids but did not show dramatic change initially. The patient eventually improved with management and was discharged. Cureus 2022-04-11 /pmc/articles/PMC9093252/ /pubmed/35573511 http://dx.doi.org/10.7759/cureus.24035 Text en Copyright © 2022, Alrefaey et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Emergency Medicine
Alrefaey, Yazeid
Alamoudi, Ahmad
Johar, Reshale
Albar, Rawia F
Multisystem Inflammatory Syndrome in Children (MIS-C) With Hematological Manifestations: A Case Report
title Multisystem Inflammatory Syndrome in Children (MIS-C) With Hematological Manifestations: A Case Report
title_full Multisystem Inflammatory Syndrome in Children (MIS-C) With Hematological Manifestations: A Case Report
title_fullStr Multisystem Inflammatory Syndrome in Children (MIS-C) With Hematological Manifestations: A Case Report
title_full_unstemmed Multisystem Inflammatory Syndrome in Children (MIS-C) With Hematological Manifestations: A Case Report
title_short Multisystem Inflammatory Syndrome in Children (MIS-C) With Hematological Manifestations: A Case Report
title_sort multisystem inflammatory syndrome in children (mis-c) with hematological manifestations: a case report
topic Emergency Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9093252/
https://www.ncbi.nlm.nih.gov/pubmed/35573511
http://dx.doi.org/10.7759/cureus.24035
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