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Case Report: Advantages of High-Resolution MRI in Evaluating the Efficacy of Drug Therapy for Intracranial Atherosclerotic Plaques

Intracranial atherosclerotic stenosis is one of the main causes of ischemic stroke and transient ischemic attack. High-resolution magnetic resonance imaging allows us to directly observe the intracranial artery wall, accurately assess the condition of the vascular wall, and quantitatively analyze th...

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Autores principales: Zheng, Tao, Liu, Lei, Li, Li, Gao, Yang, Guo, Runcai, Zhou, Zhi, Liu, Zunjing, Liu, Kunpeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9093647/
https://www.ncbi.nlm.nih.gov/pubmed/35572131
http://dx.doi.org/10.3389/fnagi.2022.804074
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author Zheng, Tao
Liu, Lei
Li, Li
Gao, Yang
Guo, Runcai
Zhou, Zhi
Liu, Zunjing
Liu, Kunpeng
author_facet Zheng, Tao
Liu, Lei
Li, Li
Gao, Yang
Guo, Runcai
Zhou, Zhi
Liu, Zunjing
Liu, Kunpeng
author_sort Zheng, Tao
collection PubMed
description Intracranial atherosclerotic stenosis is one of the main causes of ischemic stroke and transient ischemic attack. High-resolution magnetic resonance imaging allows us to directly observe the intracranial artery wall, accurately assess the condition of the vascular wall, and quantitatively analyze the vascular wall and intracranial atherosclerotic plaque load. We report a case of acute cerebral infarction with left middle cerebral artery stenosis. During the first 3 weeks, the patient was treated with aspirin 100 mg and clopidogrel 75 mg daily. Afterwards, the patient continued to be given aspirin, and cilostazol 100 mg twice daily was given instead of clopidogrel. After 24 months of follow-up, we observed a significant reversal of intracranial atherosclerotic plaque using high-resolution MRI (HR-MRI) and discussed the advantages of HR-MRI in evaluating drug therapy for intracranial atherosclerotic plaque.
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spelling pubmed-90936472022-05-12 Case Report: Advantages of High-Resolution MRI in Evaluating the Efficacy of Drug Therapy for Intracranial Atherosclerotic Plaques Zheng, Tao Liu, Lei Li, Li Gao, Yang Guo, Runcai Zhou, Zhi Liu, Zunjing Liu, Kunpeng Front Aging Neurosci Aging Neuroscience Intracranial atherosclerotic stenosis is one of the main causes of ischemic stroke and transient ischemic attack. High-resolution magnetic resonance imaging allows us to directly observe the intracranial artery wall, accurately assess the condition of the vascular wall, and quantitatively analyze the vascular wall and intracranial atherosclerotic plaque load. We report a case of acute cerebral infarction with left middle cerebral artery stenosis. During the first 3 weeks, the patient was treated with aspirin 100 mg and clopidogrel 75 mg daily. Afterwards, the patient continued to be given aspirin, and cilostazol 100 mg twice daily was given instead of clopidogrel. After 24 months of follow-up, we observed a significant reversal of intracranial atherosclerotic plaque using high-resolution MRI (HR-MRI) and discussed the advantages of HR-MRI in evaluating drug therapy for intracranial atherosclerotic plaque. Frontiers Media S.A. 2022-04-27 /pmc/articles/PMC9093647/ /pubmed/35572131 http://dx.doi.org/10.3389/fnagi.2022.804074 Text en Copyright © 2022 Zheng, Liu, Li, Gao, Guo, Zhou, Liu and Liu. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Aging Neuroscience
Zheng, Tao
Liu, Lei
Li, Li
Gao, Yang
Guo, Runcai
Zhou, Zhi
Liu, Zunjing
Liu, Kunpeng
Case Report: Advantages of High-Resolution MRI in Evaluating the Efficacy of Drug Therapy for Intracranial Atherosclerotic Plaques
title Case Report: Advantages of High-Resolution MRI in Evaluating the Efficacy of Drug Therapy for Intracranial Atherosclerotic Plaques
title_full Case Report: Advantages of High-Resolution MRI in Evaluating the Efficacy of Drug Therapy for Intracranial Atherosclerotic Plaques
title_fullStr Case Report: Advantages of High-Resolution MRI in Evaluating the Efficacy of Drug Therapy for Intracranial Atherosclerotic Plaques
title_full_unstemmed Case Report: Advantages of High-Resolution MRI in Evaluating the Efficacy of Drug Therapy for Intracranial Atherosclerotic Plaques
title_short Case Report: Advantages of High-Resolution MRI in Evaluating the Efficacy of Drug Therapy for Intracranial Atherosclerotic Plaques
title_sort case report: advantages of high-resolution mri in evaluating the efficacy of drug therapy for intracranial atherosclerotic plaques
topic Aging Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9093647/
https://www.ncbi.nlm.nih.gov/pubmed/35572131
http://dx.doi.org/10.3389/fnagi.2022.804074
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