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Translational development of a tumor junction opening technology

Our goal is to overcome treatment resistance in ovarian cancer patients which occurs in most cases after an initial positive response to chemotherapy. A central resistance mechanism is the maintenance of desmoglein-2 (DSG2) positive tight junctions between malignant cells that prevents drug penetrat...

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Detalles Bibliográficos
Autores principales: Kim, Jiho, Li, Chang, Wang, Hongjie, Kaviraj, Swarnendu, Singh, Sanjay, Savergave, Laxman, Raghuwanshi, Arjun, Gil, Sucheol, Germond, Audrey, Baldessari, Audrey, Chen, Bingmae, Roffler, Steve, Fender, Pascal, Drescher, Charles, Carter, Darrick, Lieber, André
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9094124/
https://www.ncbi.nlm.nih.gov/pubmed/35562182
http://dx.doi.org/10.1038/s41598-022-11843-z

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