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Targeting PARP1 to Enhance Anticancer Checkpoint Immunotherapy Response: Rationale and Clinical Implications
Reinvigorating the antitumor immune response using immune checkpoint inhibitors (ICIs) has revolutionized the treatment of several malignancies. However, extended use of ICIs has resulted in a cancer-specific response. In tumors considered to be less immunogenic, the response rates were low or null....
Autores principales: | Wanderley, Carlos Wagner S., Correa, Tatiana Strava, Scaranti, Mariana, Cunha, Fernando Queiroz, Barroso-Sousa, Romualdo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9094400/ https://www.ncbi.nlm.nih.gov/pubmed/35572596 http://dx.doi.org/10.3389/fimmu.2022.816642 |
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