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Secondary Complement Deficiency Impairs Anti-Microbial Immunity to Klebsiella pneumoniae and Staphylococcus aureus During Severe Acute COVID-19

A high incidence of secondary Klebsiella pneumoniae and Staphylococcus aureus infection were observed in patients with severe COVID-19. The cause of this predisposition to infection is unclear. Our data demonstrate consumption of complement in acute COVID-19 patients reflected by low levels of C3, C...

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Detalles Bibliográficos
Autores principales: Ali, Youssif M., Lynch, Nicholas J., Khatri, Priyanka, Bamigbola, Ifeoluwa E., Chan, Andrew C. Y., Yabuki, Munehisa, Demopulos, Gregory A., Heeney, Jonathan L., Pai, Sumita, Baxendale, Helen, Schwaeble, Wilhelm J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9094484/
https://www.ncbi.nlm.nih.gov/pubmed/35572551
http://dx.doi.org/10.3389/fimmu.2022.841759