Spectral homogeneity of human platelets investigated by SERS

This paper describes a detailed study of the spectral homogeneity of human platelets using Surface-enhanced Raman spectroscopy (SERS). We used a combined approach based on multivariate methods as principal component analysis and pair correlation algorithms to investigate platelets spectral propertie...

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Autores principales: Zyubin, Andrey, Rafalskiy, Vladimir, Lopatin, Mikhail, Demishkevich, Elizaveta, Moiseeva, Ekaterina, Matveeva, Karina, Kon, Igor, Khankaev, Artemii, Kundalevich, Anna, Butova, Viktoria, Lipnevich, Leonard, Lyatun, Ivan, Samusev, Ilia, Bryukhanov, Valery
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9094501/
https://www.ncbi.nlm.nih.gov/pubmed/35544536
http://dx.doi.org/10.1371/journal.pone.0265247
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author Zyubin, Andrey
Rafalskiy, Vladimir
Lopatin, Mikhail
Demishkevich, Elizaveta
Moiseeva, Ekaterina
Matveeva, Karina
Kon, Igor
Khankaev, Artemii
Kundalevich, Anna
Butova, Viktoria
Lipnevich, Leonard
Lyatun, Ivan
Samusev, Ilia
Bryukhanov, Valery
author_facet Zyubin, Andrey
Rafalskiy, Vladimir
Lopatin, Mikhail
Demishkevich, Elizaveta
Moiseeva, Ekaterina
Matveeva, Karina
Kon, Igor
Khankaev, Artemii
Kundalevich, Anna
Butova, Viktoria
Lipnevich, Leonard
Lyatun, Ivan
Samusev, Ilia
Bryukhanov, Valery
author_sort Zyubin, Andrey
collection PubMed
description This paper describes a detailed study of the spectral homogeneity of human platelets using Surface-enhanced Raman spectroscopy (SERS). We used a combined approach based on multivariate methods as principal component analysis and pair correlation algorithms to investigate platelets spectral properties. The correlation coefficients for each sample have been calculated, and the average coefficient of determination has been estimated. The high degree of spectral homogeneity inside one probe and between them has been revealed. The prospects of obtained results usage for pathologies based on platelet conformations during cardiovascular diseases have been demonstrated.
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spelling pubmed-90945012022-05-12 Spectral homogeneity of human platelets investigated by SERS Zyubin, Andrey Rafalskiy, Vladimir Lopatin, Mikhail Demishkevich, Elizaveta Moiseeva, Ekaterina Matveeva, Karina Kon, Igor Khankaev, Artemii Kundalevich, Anna Butova, Viktoria Lipnevich, Leonard Lyatun, Ivan Samusev, Ilia Bryukhanov, Valery PLoS One Research Article This paper describes a detailed study of the spectral homogeneity of human platelets using Surface-enhanced Raman spectroscopy (SERS). We used a combined approach based on multivariate methods as principal component analysis and pair correlation algorithms to investigate platelets spectral properties. The correlation coefficients for each sample have been calculated, and the average coefficient of determination has been estimated. The high degree of spectral homogeneity inside one probe and between them has been revealed. The prospects of obtained results usage for pathologies based on platelet conformations during cardiovascular diseases have been demonstrated. Public Library of Science 2022-05-11 /pmc/articles/PMC9094501/ /pubmed/35544536 http://dx.doi.org/10.1371/journal.pone.0265247 Text en © 2022 Zyubin et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Zyubin, Andrey
Rafalskiy, Vladimir
Lopatin, Mikhail
Demishkevich, Elizaveta
Moiseeva, Ekaterina
Matveeva, Karina
Kon, Igor
Khankaev, Artemii
Kundalevich, Anna
Butova, Viktoria
Lipnevich, Leonard
Lyatun, Ivan
Samusev, Ilia
Bryukhanov, Valery
Spectral homogeneity of human platelets investigated by SERS
title Spectral homogeneity of human platelets investigated by SERS
title_full Spectral homogeneity of human platelets investigated by SERS
title_fullStr Spectral homogeneity of human platelets investigated by SERS
title_full_unstemmed Spectral homogeneity of human platelets investigated by SERS
title_short Spectral homogeneity of human platelets investigated by SERS
title_sort spectral homogeneity of human platelets investigated by sers
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9094501/
https://www.ncbi.nlm.nih.gov/pubmed/35544536
http://dx.doi.org/10.1371/journal.pone.0265247
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