Polyamine biosynthesis and eIF5A hypusination are modulated by the DNA tumor virus KSHV and promote KSHV viral infection

Polyamines are critical metabolites involved in various cellular processes and often dysregulated in cancers. Kaposi’s sarcoma-associated Herpesvirus (KSHV), a defined human oncogenic virus, leads to profound alterations of host metabolic landscape to favor development of KSHV-associated malignancie...

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Detalles Bibliográficos
Autores principales: Fiches, Guillaume N., Wu, Zhenyu, Zhou, Dawei, Biswas, Ayan, Li, Tai-Wei, Kong, Weili, Jean, Maxime, Santoso, Netty G., Zhu, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9094511/
https://www.ncbi.nlm.nih.gov/pubmed/35486659
http://dx.doi.org/10.1371/journal.ppat.1010503

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