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α-Phenylalanyl tRNA synthetase competes with Notch signaling through its N-terminal domain

The alpha subunit of the cytoplasmic Phenylalanyl tRNA synthetase (α-PheRS, FARSA in humans) displays cell growth and proliferation activities and its elevated levels can induce cell fate changes and tumor-like phenotypes that are neither dependent on the canonical function of charging tRNA(Phe) wit...

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Detalles Bibliográficos
Autores principales:	Ho, Manh Tin, Lu, Jiongming, Vazquez-Pianzola, Paula, Suter, Beat
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9094542/ https://www.ncbi.nlm.nih.gov/pubmed/35486661 http://dx.doi.org/10.1371/journal.pgen.1010185

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