Cargando…
Prevalence of specific micronutrient deficiencies in urban school going children and adolescence of India: A multicenter cross-sectional study
INTRODUCTION: Childhood and adolescence require adequate amount of micronutrients for normal growth and development. The primary objective of study was to assess the prevalence of deficiencies of Vitamins (Vitamin A, 25 Hydroxy Vitamin D, Vitamin B12 and Folate) and minerals (Calcium, Zinc, Selenium...
Autores principales: | , , , , , , , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9094555/ https://www.ncbi.nlm.nih.gov/pubmed/35544476 http://dx.doi.org/10.1371/journal.pone.0267003 |
_version_ | 1784705564626911232 |
---|---|
author | Awasthi, Shally Kumar, Divas Mahdi, Abbas Ali Agarwal, Girdhar G. Pandey, Anuj Kumar Parveen, Hina Singh, Shweta Awasthi, Rajiv Pande, Harsh T. S., Anish Mahanta, B. N. Singh, C. M. Mathew, Joseph L. Ahmad, Mohammad Kaleem Singh, Kuldeep Bhat, Mushtaq A. A. R., Somashekar Kar, Sonali Nair, Suma |
author_facet | Awasthi, Shally Kumar, Divas Mahdi, Abbas Ali Agarwal, Girdhar G. Pandey, Anuj Kumar Parveen, Hina Singh, Shweta Awasthi, Rajiv Pande, Harsh T. S., Anish Mahanta, B. N. Singh, C. M. Mathew, Joseph L. Ahmad, Mohammad Kaleem Singh, Kuldeep Bhat, Mushtaq A. A. R., Somashekar Kar, Sonali Nair, Suma |
author_sort | Awasthi, Shally |
collection | PubMed |
description | INTRODUCTION: Childhood and adolescence require adequate amount of micronutrients for normal growth and development. The primary objective of study was to assess the prevalence of deficiencies of Vitamins (Vitamin A, 25 Hydroxy Vitamin D, Vitamin B12 and Folate) and minerals (Calcium, Zinc, Selenium and Iron), among urban school going children aged 6–11 and 12–16 years in ten cities of India. Secondary objective was to find the association between micronutrient deficiencies with sociodemographic and anthropometric indicators. METHODS: A multi-center cross-sectional study was conducted across India. Participants in the age groups of 6 to 11 years (group 1) and 12 to 16 years (group 2) were selected from randomly chosen schools from each center. Data on socio economic status, anthropometric measures was collected. Blood samples were collected for biochemical analysis of micronutrients. Point estimates and 95% confidence intervals was used to assess the prevalence of deficiencies. Associations were observed using chi square, student t test and ANOVA test. RESULTS: From April 2019 to February 2020, 2428 participants (1235 in group 1 and 1193 group 2) were recruited from 60 schools across ten cites. The prevalence of calcium and iron deficiency was 59.9% and 49.4% respectively. 25 Hydroxy Vitamin D deficiency was seen in 39.7% and vitamin B12 in 33.4% of subjects. Folate, Selenium and Zinc were deficient in 22.2%, 10.4% and 6.8% of subjects respectively. Vitamin A deficiency least (1.6%). Anemia was prevalent in 17.6% subjects and was more common among females. CONCLUSION: One or more micronutrient deficiencies are found in almost one half of school going children in urban area. Hence efforts must be made to combat these on priority. TRIAL REGISTRATION NUMBER: CTRI/2019/02/017783. |
format | Online Article Text |
id | pubmed-9094555 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-90945552022-05-12 Prevalence of specific micronutrient deficiencies in urban school going children and adolescence of India: A multicenter cross-sectional study Awasthi, Shally Kumar, Divas Mahdi, Abbas Ali Agarwal, Girdhar G. Pandey, Anuj Kumar Parveen, Hina Singh, Shweta Awasthi, Rajiv Pande, Harsh T. S., Anish Mahanta, B. N. Singh, C. M. Mathew, Joseph L. Ahmad, Mohammad Kaleem Singh, Kuldeep Bhat, Mushtaq A. A. R., Somashekar Kar, Sonali Nair, Suma PLoS One Research Article INTRODUCTION: Childhood and adolescence require adequate amount of micronutrients for normal growth and development. The primary objective of study was to assess the prevalence of deficiencies of Vitamins (Vitamin A, 25 Hydroxy Vitamin D, Vitamin B12 and Folate) and minerals (Calcium, Zinc, Selenium and Iron), among urban school going children aged 6–11 and 12–16 years in ten cities of India. Secondary objective was to find the association between micronutrient deficiencies with sociodemographic and anthropometric indicators. METHODS: A multi-center cross-sectional study was conducted across India. Participants in the age groups of 6 to 11 years (group 1) and 12 to 16 years (group 2) were selected from randomly chosen schools from each center. Data on socio economic status, anthropometric measures was collected. Blood samples were collected for biochemical analysis of micronutrients. Point estimates and 95% confidence intervals was used to assess the prevalence of deficiencies. Associations were observed using chi square, student t test and ANOVA test. RESULTS: From April 2019 to February 2020, 2428 participants (1235 in group 1 and 1193 group 2) were recruited from 60 schools across ten cites. The prevalence of calcium and iron deficiency was 59.9% and 49.4% respectively. 25 Hydroxy Vitamin D deficiency was seen in 39.7% and vitamin B12 in 33.4% of subjects. Folate, Selenium and Zinc were deficient in 22.2%, 10.4% and 6.8% of subjects respectively. Vitamin A deficiency least (1.6%). Anemia was prevalent in 17.6% subjects and was more common among females. CONCLUSION: One or more micronutrient deficiencies are found in almost one half of school going children in urban area. Hence efforts must be made to combat these on priority. TRIAL REGISTRATION NUMBER: CTRI/2019/02/017783. Public Library of Science 2022-05-11 /pmc/articles/PMC9094555/ /pubmed/35544476 http://dx.doi.org/10.1371/journal.pone.0267003 Text en © 2022 Awasthi et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Awasthi, Shally Kumar, Divas Mahdi, Abbas Ali Agarwal, Girdhar G. Pandey, Anuj Kumar Parveen, Hina Singh, Shweta Awasthi, Rajiv Pande, Harsh T. S., Anish Mahanta, B. N. Singh, C. M. Mathew, Joseph L. Ahmad, Mohammad Kaleem Singh, Kuldeep Bhat, Mushtaq A. A. R., Somashekar Kar, Sonali Nair, Suma Prevalence of specific micronutrient deficiencies in urban school going children and adolescence of India: A multicenter cross-sectional study |
title | Prevalence of specific micronutrient deficiencies in urban school going children and adolescence of India: A multicenter cross-sectional study |
title_full | Prevalence of specific micronutrient deficiencies in urban school going children and adolescence of India: A multicenter cross-sectional study |
title_fullStr | Prevalence of specific micronutrient deficiencies in urban school going children and adolescence of India: A multicenter cross-sectional study |
title_full_unstemmed | Prevalence of specific micronutrient deficiencies in urban school going children and adolescence of India: A multicenter cross-sectional study |
title_short | Prevalence of specific micronutrient deficiencies in urban school going children and adolescence of India: A multicenter cross-sectional study |
title_sort | prevalence of specific micronutrient deficiencies in urban school going children and adolescence of india: a multicenter cross-sectional study |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9094555/ https://www.ncbi.nlm.nih.gov/pubmed/35544476 http://dx.doi.org/10.1371/journal.pone.0267003 |
work_keys_str_mv | AT awasthishally prevalenceofspecificmicronutrientdeficienciesinurbanschoolgoingchildrenandadolescenceofindiaamulticentercrosssectionalstudy AT kumardivas prevalenceofspecificmicronutrientdeficienciesinurbanschoolgoingchildrenandadolescenceofindiaamulticentercrosssectionalstudy AT mahdiabbasali prevalenceofspecificmicronutrientdeficienciesinurbanschoolgoingchildrenandadolescenceofindiaamulticentercrosssectionalstudy AT agarwalgirdharg prevalenceofspecificmicronutrientdeficienciesinurbanschoolgoingchildrenandadolescenceofindiaamulticentercrosssectionalstudy AT pandeyanujkumar prevalenceofspecificmicronutrientdeficienciesinurbanschoolgoingchildrenandadolescenceofindiaamulticentercrosssectionalstudy AT parveenhina prevalenceofspecificmicronutrientdeficienciesinurbanschoolgoingchildrenandadolescenceofindiaamulticentercrosssectionalstudy AT singhshweta prevalenceofspecificmicronutrientdeficienciesinurbanschoolgoingchildrenandadolescenceofindiaamulticentercrosssectionalstudy AT awasthirajiv prevalenceofspecificmicronutrientdeficienciesinurbanschoolgoingchildrenandadolescenceofindiaamulticentercrosssectionalstudy AT pandeharsh prevalenceofspecificmicronutrientdeficienciesinurbanschoolgoingchildrenandadolescenceofindiaamulticentercrosssectionalstudy AT tsanish prevalenceofspecificmicronutrientdeficienciesinurbanschoolgoingchildrenandadolescenceofindiaamulticentercrosssectionalstudy AT mahantabn prevalenceofspecificmicronutrientdeficienciesinurbanschoolgoingchildrenandadolescenceofindiaamulticentercrosssectionalstudy AT singhcm prevalenceofspecificmicronutrientdeficienciesinurbanschoolgoingchildrenandadolescenceofindiaamulticentercrosssectionalstudy AT mathewjosephl prevalenceofspecificmicronutrientdeficienciesinurbanschoolgoingchildrenandadolescenceofindiaamulticentercrosssectionalstudy AT ahmadmohammadkaleem prevalenceofspecificmicronutrientdeficienciesinurbanschoolgoingchildrenandadolescenceofindiaamulticentercrosssectionalstudy AT singhkuldeep prevalenceofspecificmicronutrientdeficienciesinurbanschoolgoingchildrenandadolescenceofindiaamulticentercrosssectionalstudy AT bhatmushtaqa prevalenceofspecificmicronutrientdeficienciesinurbanschoolgoingchildrenandadolescenceofindiaamulticentercrosssectionalstudy AT arsomashekar prevalenceofspecificmicronutrientdeficienciesinurbanschoolgoingchildrenandadolescenceofindiaamulticentercrosssectionalstudy AT karsonali prevalenceofspecificmicronutrientdeficienciesinurbanschoolgoingchildrenandadolescenceofindiaamulticentercrosssectionalstudy AT nairsuma prevalenceofspecificmicronutrientdeficienciesinurbanschoolgoingchildrenandadolescenceofindiaamulticentercrosssectionalstudy |