A randomized clinical trial demonstrating cell type specific effects of hyperlipidemia and hyperinsulinemia on pituitary function

INTRODUCTION: Obesity is characterized by elevated lipids, insulin resistance and relative hypogonadotropic hypogonadism, reducing fertility and increasing risk of pregnancy complications and birth defects. We termed this phenotype ‘Reprometabolic Syndrome’ and showed that it can be recapitulated by...

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Detalles Bibliográficos
Autores principales: McDonald, Rosemary, Kuhn, Katherine, Nguyen, Thy B., Tannous, Andrew, Schauer, Irene, Santoro, Nanette, Bradford, Andrew P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9094557/
https://www.ncbi.nlm.nih.gov/pubmed/35544473
http://dx.doi.org/10.1371/journal.pone.0268323

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