Neurophysiological effects of human-derived pathological tau conformers in the APPKM670/671NL.PS1/L166P amyloid mouse model of Alzheimer’s disease

Alzheimer’s Disease (AD) is a neurodegenerative disease characterized by two main pathological hallmarks: amyloid plaques and intracellular tau neurofibrillary tangles. However, a majority of studies focus on the individual pathologies and seldom on the interaction between the two pathologies. Herei...

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Detalles Bibliográficos
Autores principales: Tok, S., Maurin, H., Delay, C., Crauwels, D., Manyakov, N. V., Van Der Elst, W., Moechars, D., Drinkenburg, W. H. I. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9094605/
https://www.ncbi.nlm.nih.gov/pubmed/35546164
http://dx.doi.org/10.1038/s41598-022-11582-1

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