Tankyrase-mediated ADP-ribosylation is a regulator of TNF-induced death

Tumor necrosis factor (TNF) is a key component of the innate immune response. Upon binding to its receptor, TNFR1, it promotes production of other cytokines via a membrane-bound complex 1 or induces cell death via a cytosolic complex 2. To understand how TNF-induced cell death is regulated, we perfo...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Lin, Sandow, Jarrod J., Leslie Pedrioli, Deena M., Samson, Andre L., Silke, Natasha, Kratina, Tobias, Ambrose, Rebecca L., Doerflinger, Marcel, Hu, Zhaoqing, Morrish, Emma, Chau, Diep, Kueh, Andrew J., Fitzibbon, Cheree, Pellegrini, Marc, Pearson, Jaclyn S., Hottiger, Michael O., Webb, Andrew I., Lalaoui, Najoua, Silke, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9094663/
https://www.ncbi.nlm.nih.gov/pubmed/35544574
http://dx.doi.org/10.1126/sciadv.abh2332

Ejemplares similares

Ejemplares similares