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DNA Methylation Analysis of Ribosomal DNA in Adults With Down Syndrome

Control of ribosome biogenesis is a critical aspect of the regulation of cell metabolism. As ribosomal genes (rDNA) are organized in repeated clusters on chromosomes 13, 14, 15, 21, and 22, trisomy of chromosome 21 confers an excess of rDNA copies to persons with Down syndrome (DS). Previous studies...

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Detalles Bibliográficos
Autores principales:	Ravaioli, Francesco, Zampieri, Michele, Morandi, Luca, Pirazzini, Chiara, Pellegrini, Camilla, De Fanti, Sara, Gensous, Noémie, Pirazzoli, Gian Luca, Sambati, Luisa, Ghezzo, Alessandro, Ciccarone, Fabio, Reale, Anna, Monti, Daniela, Salvioli, Stefano, Caiafa, Paola, Capri, Miriam, Bürkle, Alexander, Moreno-Villanueva, Maria, Garagnani, Paolo, Franceschi, Claudio, Bacalini, Maria Giulia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9094685/ https://www.ncbi.nlm.nih.gov/pubmed/35571061 http://dx.doi.org/10.3389/fgene.2022.792165

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