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Pediatric Subarachnoid Hemorrhage: Rare Events with Important Implications

Rupture of an aneurysm is the leading cause of subarachnoid hemorrhage (SAH) which results in accumulation of blood between the arachnoid and pia mater, consequently increasing intracranial pressure. This often results in life threatening conditions like herniation or clinical presentations includin...

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Autores principales: Dagra, Abeer, Williams, Eric, Aghili-Mehrizi, Sina, Goutnik, Michael A, Martinez, Melanie, Turner, Ryan C, Lucke-Wold, Brandon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9094715/
https://www.ncbi.nlm.nih.gov/pubmed/35557982
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author Dagra, Abeer
Williams, Eric
Aghili-Mehrizi, Sina
Goutnik, Michael A
Martinez, Melanie
Turner, Ryan C
Lucke-Wold, Brandon
author_facet Dagra, Abeer
Williams, Eric
Aghili-Mehrizi, Sina
Goutnik, Michael A
Martinez, Melanie
Turner, Ryan C
Lucke-Wold, Brandon
author_sort Dagra, Abeer
collection PubMed
description Rupture of an aneurysm is the leading cause of subarachnoid hemorrhage (SAH) which results in accumulation of blood between the arachnoid and pia mater, consequently increasing intracranial pressure. This often results in life threatening conditions like herniation or clinical presentations including focal neurological deficits. In children, these events, although rare, have significant implications. Pediatric SAH is associated with better outcomes in the hospital setting and may even be prevented proactively by the recognition of potential risk factors. Specifically, better recognition of genetic predispositions, metastatic lesions, and infectious causes of aneurysms is important to understand their growth and prevent hemorrhagic events. This review highlights the causes of pediatric SAH, reviews the models of current understanding of this etiology, and discusses the current treatment schema to provide a succinct summary and highlight gaps in current knowledge. This may lead to future investigations aimed at further improving prevention strategies, patient care, and patient outcomes.
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spelling pubmed-90947152022-05-11 Pediatric Subarachnoid Hemorrhage: Rare Events with Important Implications Dagra, Abeer Williams, Eric Aghili-Mehrizi, Sina Goutnik, Michael A Martinez, Melanie Turner, Ryan C Lucke-Wold, Brandon Brain Neurol Disord Article Rupture of an aneurysm is the leading cause of subarachnoid hemorrhage (SAH) which results in accumulation of blood between the arachnoid and pia mater, consequently increasing intracranial pressure. This often results in life threatening conditions like herniation or clinical presentations including focal neurological deficits. In children, these events, although rare, have significant implications. Pediatric SAH is associated with better outcomes in the hospital setting and may even be prevented proactively by the recognition of potential risk factors. Specifically, better recognition of genetic predispositions, metastatic lesions, and infectious causes of aneurysms is important to understand their growth and prevent hemorrhagic events. This review highlights the causes of pediatric SAH, reviews the models of current understanding of this etiology, and discusses the current treatment schema to provide a succinct summary and highlight gaps in current knowledge. This may lead to future investigations aimed at further improving prevention strategies, patient care, and patient outcomes. 2022 2022-03-14 /pmc/articles/PMC9094715/ /pubmed/35557982 Text en https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Article
Dagra, Abeer
Williams, Eric
Aghili-Mehrizi, Sina
Goutnik, Michael A
Martinez, Melanie
Turner, Ryan C
Lucke-Wold, Brandon
Pediatric Subarachnoid Hemorrhage: Rare Events with Important Implications
title Pediatric Subarachnoid Hemorrhage: Rare Events with Important Implications
title_full Pediatric Subarachnoid Hemorrhage: Rare Events with Important Implications
title_fullStr Pediatric Subarachnoid Hemorrhage: Rare Events with Important Implications
title_full_unstemmed Pediatric Subarachnoid Hemorrhage: Rare Events with Important Implications
title_short Pediatric Subarachnoid Hemorrhage: Rare Events with Important Implications
title_sort pediatric subarachnoid hemorrhage: rare events with important implications
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9094715/
https://www.ncbi.nlm.nih.gov/pubmed/35557982
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