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Detection of malignant peripheral nerve sheath tumors in patients with neurofibromatosis using aneuploidy and mutation identification in plasma

Malignant peripheral nerve sheath tumors (MPNST) are the deadliest cancer that arises in individuals diagnosed with neurofibromatosis and account for nearly 5% of the 15,000 soft tissue sarcomas diagnosed in the United States each year. Comprised of neoplastic Schwann cells, primary risk factors for...

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Detalles Bibliográficos
Autores principales: Mattox, Austin K, Douville, Christopher, Silliman, Natalie, Ptak, Janine, Dobbyn, Lisa, Schaefer, Joy, Popoli, Maria, Blair, Cherie, Judge, Kathy, Pollard, Kai, Pratilas, Christine, Blakeley, Jaishri, Rodriguez, Fausto, Papadopoulos, Nickolas, Belzberg, Allan, Bettegowda, Chetan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9094745/
https://www.ncbi.nlm.nih.gov/pubmed/35244537
http://dx.doi.org/10.7554/eLife.74238