Allosteric cooperation in β-lactam binding to a non-classical transpeptidase

L,D-transpeptidase function predominates in atypical 3 → 3 transpeptide networking of peptidoglycan (PG) layer in Mycobacterium tuberculosis. Prior studies of L,D-transpeptidases have identified only the catalytic site that binds to peptide moiety of the PG substrate or β-lactam antibiotics. This in...

Descripción completa

Detalles Bibliográficos
Autores principales: Ahmad, Nazia, Dugad, Sanmati, Chauhan, Varsha, Ahmed, Shubbir, Sharma, Kunal, Kachhap, Sangita, Zaidi, Rana, Bishai, William R, Lamichhane, Gyanu, Kumar, Pankaj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Biochemistry and Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9094749/
https://www.ncbi.nlm.nih.gov/pubmed/35475970
http://dx.doi.org/10.7554/eLife.73055

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9094749/
https://www.ncbi.nlm.nih.gov/pubmed/35475970
http://dx.doi.org/10.7554/eLife.73055

Ejemplares similares