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Measuring the tolerance of the genetic code to altered codon size
Translation using four-base codons occurs in both natural and synthetic systems. What constraints contributed to the universal adoption of a triplet codon, rather than quadruplet codon, genetic code? Here, we investigate the tolerance of the Escherichia coli genetic code to tRNA mutations that incre...
Autores principales: | DeBenedictis, Erika Alden, Söll, Dieter, Esvelt, Kevin M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9094753/ https://www.ncbi.nlm.nih.gov/pubmed/35293861 http://dx.doi.org/10.7554/eLife.76941 |
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