Macrophage inflammation resolution requires CPEB4-directed offsetting of mRNA degradation

Chronic inflammation is a major cause of disease. Inflammation resolution is in part directed by the differential stability of mRNAs encoding pro-inflammatory and anti-inflammatory factors. In particular, tristetraprolin (TTP)-directed mRNA deadenylation destabilizes AU-rich element (ARE)-containing...

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Detalles Bibliográficos
Autores principales: Suñer, Clara, Sibilio, Annarita, Martín, Judit, Castellazzi, Chiara Lara, Reina, Oscar, Dotu, Ivan, Caballé, Adrià, Rivas, Elisa, Calderone, Vittorio, Díez, Juana, Nebreda, Angel R, Méndez, Raúl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9094754/
https://www.ncbi.nlm.nih.gov/pubmed/35442882
http://dx.doi.org/10.7554/eLife.75873

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9094754/
https://www.ncbi.nlm.nih.gov/pubmed/35442882
http://dx.doi.org/10.7554/eLife.75873

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