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Increased airborne transmission of COVID-19 with new variants, implications for health policies
New COVID-19 variants, either of higher viral load such as delta or higher contagiousness like omicron, can lead to higher airborne transmission than historical strains. This paper highlights their implications for health policies, based on a clear analytical understanding and modeling of the airbor...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Ltd.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9095081/ https://www.ncbi.nlm.nih.gov/pubmed/35578697 http://dx.doi.org/10.1016/j.buildenv.2022.109132 |
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author | Rowe, Bertrand R. Canosa, André Meslem, Amina Rowe, Frantz |
author_facet | Rowe, Bertrand R. Canosa, André Meslem, Amina Rowe, Frantz |
author_sort | Rowe, Bertrand R. |
collection | PubMed |
description | New COVID-19 variants, either of higher viral load such as delta or higher contagiousness like omicron, can lead to higher airborne transmission than historical strains. This paper highlights their implications for health policies, based on a clear analytical understanding and modeling of the airborne contamination paths, of the dose following exposure, and the importance of the counting unit for pathogens, itself linked to the dose-response law. Using the counting unit of Wells, i.e. the quantum of contagium, we develop the conservation equation of quanta which allows deriving the value of the quantum concentration at steady state for a well-mixed room. The link with the monitoring concentration of carbon dioxide is made and used for a risk analysis of a variety of situations for which we collected CO(2) time-series observations. The main conclusions of these observations are that 1) the present norms of ventilation, are both insufficient and not respected, especially in a variety of public premises, leading to high risk of contamination and that 2) air can often be considered well-mixed. Finally, we insist that public health policy in the field of airborne transmission should be based on a multi parameter analysis such as the time of exposure, the quantum production rate, mask wearing and the infector proportion in the population in order to evaluate the risk, considering the whole complexity of dose evaluation. Recognizing airborne transmission requires thinking in terms of time of exposure rather than in terms of proximal distance. |
format | Online Article Text |
id | pubmed-9095081 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Elsevier Ltd. |
record_format | MEDLINE/PubMed |
spelling | pubmed-90950812022-05-12 Increased airborne transmission of COVID-19 with new variants, implications for health policies Rowe, Bertrand R. Canosa, André Meslem, Amina Rowe, Frantz Build Environ Article New COVID-19 variants, either of higher viral load such as delta or higher contagiousness like omicron, can lead to higher airborne transmission than historical strains. This paper highlights their implications for health policies, based on a clear analytical understanding and modeling of the airborne contamination paths, of the dose following exposure, and the importance of the counting unit for pathogens, itself linked to the dose-response law. Using the counting unit of Wells, i.e. the quantum of contagium, we develop the conservation equation of quanta which allows deriving the value of the quantum concentration at steady state for a well-mixed room. The link with the monitoring concentration of carbon dioxide is made and used for a risk analysis of a variety of situations for which we collected CO(2) time-series observations. The main conclusions of these observations are that 1) the present norms of ventilation, are both insufficient and not respected, especially in a variety of public premises, leading to high risk of contamination and that 2) air can often be considered well-mixed. Finally, we insist that public health policy in the field of airborne transmission should be based on a multi parameter analysis such as the time of exposure, the quantum production rate, mask wearing and the infector proportion in the population in order to evaluate the risk, considering the whole complexity of dose evaluation. Recognizing airborne transmission requires thinking in terms of time of exposure rather than in terms of proximal distance. Elsevier Ltd. 2022-07-01 2022-05-12 /pmc/articles/PMC9095081/ /pubmed/35578697 http://dx.doi.org/10.1016/j.buildenv.2022.109132 Text en © 2022 Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Article Rowe, Bertrand R. Canosa, André Meslem, Amina Rowe, Frantz Increased airborne transmission of COVID-19 with new variants, implications for health policies |
title | Increased airborne transmission of COVID-19 with new variants, implications for health policies |
title_full | Increased airborne transmission of COVID-19 with new variants, implications for health policies |
title_fullStr | Increased airborne transmission of COVID-19 with new variants, implications for health policies |
title_full_unstemmed | Increased airborne transmission of COVID-19 with new variants, implications for health policies |
title_short | Increased airborne transmission of COVID-19 with new variants, implications for health policies |
title_sort | increased airborne transmission of covid-19 with new variants, implications for health policies |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9095081/ https://www.ncbi.nlm.nih.gov/pubmed/35578697 http://dx.doi.org/10.1016/j.buildenv.2022.109132 |
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