Epigenome-wide association study of alcohol consumption in N = 8161 individuals and relevance to alcohol use disorder pathophysiology: identification of the cystine/glutamate transporter SLC7A11 as a top target

Alcohol misuse is common in many societies worldwide and is associated with extensive morbidity and mortality, often leading to alcohol use disorders (AUD) and alcohol-related end-organ damage. The underlying mechanisms contributing to the development of AUD are largely unknown; however, growing evi...

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Detalles Bibliográficos
Autores principales: Lohoff, Falk W., Clarke, Toni-Kim, Kaminsky, Zachary A., Walker, Rosie M., Bermingham, Mairead L., Jung, Jeesun, Morris, Stewart W., Rosoff, Daniel, Campbell, Archie, Barbu, Miruna, Charlet, Katrin, Adams, Mark, Lee, Jisoo, Howard, David M., O’Connell, Emma M., Whalley, Heather, Porteous, David J., McIntosh, Andrew M., Evans, Kathryn L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9095480/
https://www.ncbi.nlm.nih.gov/pubmed/34857913
http://dx.doi.org/10.1038/s41380-021-01378-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9095480/
https://www.ncbi.nlm.nih.gov/pubmed/34857913
http://dx.doi.org/10.1038/s41380-021-01378-6

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