Cargando…

Identification of Synaptic DGKθ Interactors That Stimulate DGKθ Activity

Lipids and their metabolic enzymes are a critical point of regulation for the membrane curvature required to induce membrane fusion during synaptic vesicle recycling. One such enzyme is diacylglycerol kinase θ (DGKθ), which produces phosphatidic acid (PtdOH) that generates negative membrane curvatur...

Descripción completa

Detalles Bibliográficos
Autores principales:	Barber, Casey N., Goldschmidt, Hana L., Ma, Qianqian, Devine, Lauren R., Cole, Robert N., Huganir, Richard L., Raben, Daniel M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Synaptic Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9095502/ https://www.ncbi.nlm.nih.gov/pubmed/35573662 http://dx.doi.org/10.3389/fnsyn.2022.855673

Ejemplares similares

DGK-θ: Structure, Enzymology, and Physiological Roles
por: Tu-Sekine, Becky, et al.
Publicado: (2016)

Establishment of a novel hepatic steatosis cell model by Cas9/sgRNA-mediated DGKθ gene knockout
por: Zhang, Jingjing, et al.
Publicado: (2018)

Essential Role of Neuron-Enriched Diacylglycerol Kinase (DGK), DGKβ in Neurite Spine Formation, Contributing to Cognitive Function
por: Shirai, Yasuhito, et al.
Publicado: (2010)

DGKζ exerts greater control than DGKα over CD8(+) T cell activity and tumor inhibition
por: Gu, Junchen, et al.
Publicado: (2021)

DGK-α keeps integrins close to the edge
por: Mitch, Leslie
Publicado: (2012)

Mitteilungen des BCD und der DGK
Publicado: (2022)

DGKα in Neutrophil Biology and Its Implications for Respiratory Diseases
por: Baldanzi, Gianluca, et al.
Publicado: (2019)

Identification of a novel DGKα inhibitor for XLP-1 therapy by virtual screening
por: Velnati, Suresh, et al.
Publicado: (2018)

On θ(ω) continuity
por: Al Ghour, Samer, et al.
Publicado: (2020)

ENaC regulation by phospholipids and DGK explained through mathematical modeling
por: Olivença, Daniel V., et al.
Publicado: (2020)

DGKζ Plays Crucial Roles in the Proliferation and Tumorigenicity of Human glioblastoma
por: Gu, Xuefeng, et al.
Publicado: (2019)

Diagnosis and treatment of cardiac amyloidosis: position statement of the German Cardiac Society (DGK)
por: Yilmaz, A., et al.
Publicado: (2021)

SNX27 links DGKζ to the control of transcriptional and metabolic programs in T lymphocytes
por: Tello-Lafoz, M., et al.
Publicado: (2017)

DGK-α: A Checkpoint in Cancer-Mediated Immuno-Inhibition and Target for Immunotherapy
por: Noessner, Elfriede
Publicado: (2017)

Involvement of hpap2 and dgkA Genes in Colistin Resistance Mediated by mcr Determinants
por: Gallardo, Alejandro, et al.
Publicado: (2020)

Precise Regulation of the Basal PKCγ Activity by DGKγ Is Crucial for Motor Coordination
por: Tsumagari, Ryosuke, et al.
Publicado: (2020)

DGK α and ζ Activities Control T(H)1 and T(H)17 Cell Differentiation
por: Yang, Jialong, et al.
Publicado: (2020)

DGK and DZHK position paper on genome editing: basic science applications and future perspective
por: Brandes, Ralf P., et al.
Publicado: (2021)

ERK3 and DGKζ interact to modulate cell motility in lung cancer cells
por: Myers, Amanda K., et al.
Publicado: (2023)

DGKα/ζ inhibition lowers the TCR affinity threshold and potentiates antitumor immunity
por: Kureshi, Rakeeb, et al.
Publicado: (2023)

Protein Kinase C-θ (PKC-θ) in Natural Killer Cell Function and Anti-Tumor Immunity
por: Anel, Alberto, et al.
Publicado: (2012)

Cosϑ magnet design option
por: Lorin, C
Publicado: (2015)

Intervention of PKC-θ as an immunosuppressive regimen
por: Sun, Zuoming
Publicado: (2012)

Synthetic Lethality Targeting Polθ
por: Drzewiecka, Małgorzata, et al.
Publicado: (2022)

Multifaceted Nature of DNA Polymerase θ
por: Kruchinin, Alexander A., et al.
Publicado: (2023)

Delivering Glioblastoma a Kick—DGKα Inhibition as a Promising Therapeutic Strategy for GBM
por: Purow, Benjamin
Publicado: (2022)

Structure activity relationship studies on Amb639752: toward the identification of a common pharmacophoric structure for DGKα inhibitors
por: Velnati, Suresh, et al.
Publicado: (2019)

Aberrant Synaptic PTEN in Symptomatic Alzheimer’s Patients May Link Synaptic Depression to Network Failure
por: Díaz González, Marta, et al.
Publicado: (2021)

Regulating the Regulator: Phosphorylation of PKC θ in T Cells
por: Freeley, Michael, et al.
Publicado: (2012)

The Novel PKCθ from Benchtop to Clinic
por: Hage-Sleiman, Rouba, et al.
Publicado: (2015)

Discrete Symmetries and Neutrino Mass Perturbations for θ$_{13}$
por: Hall, L J, et al.
Publicado: (2013)

PKCθ Signals Activation versus Tolerance In Vivo
por: Berg-Brown, Nancy N., et al.
Publicado: (2004)

A Drosophila chemical screen reveals synergistic effect of MEK and DGKα inhibition in Ras-driven cancer
por: La Marca, John E., et al.
Publicado: (2023)

MicroRNA-132 regulates recognition memory and synaptic plasticity in the perirhinal cortex
por: Scott, Helen L, et al.
Publicado: (2012)

Fetal Neuroprotective Strategies: Therapeutic Agents and Their Underlying Synaptic Pathways
por: Elsayed, Nada A., et al.
Publicado: (2021)

DGKδ triggers endoplasmic reticulum release of IFT88-containing vesicles destined for the assembly of primary cilia
por: Ding, Jie, et al.
Publicado: (2017)

DGKα, Bridging Membrane Shape Changes with Specific Molecular Species of DAG/PA: Implications in Cancer and Immunosurveillance
por: Bozelli, José Carlos, et al.
Publicado: (2022)

Promiscuous DNA synthesis by human DNA polymerase θ
por: Hogg, Matthew, et al.
Publicado: (2012)

Precision measurements of mW and sin2θ
por: Vesterinen, Mika Anton
Publicado: (2022)

Polymerase θ inhibition steps on the cGAS pedal
por: Smith, Chelsea M., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_lulivi81oqeciaggnd05eun2ec