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Biomarkers Predicting Tissue Pharmacokinetics of Antimicrobials in Sepsis: A Review
The pathophysiology of sepsis alters drug pharmacokinetics, resulting in inadequate drug exposure and target-site concentration. Suboptimal exposure leads to treatment failure and the development of antimicrobial resistance. Therefore, we seek to optimize antimicrobial therapy in sepsis by selecting...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer International Publishing
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9095522/ https://www.ncbi.nlm.nih.gov/pubmed/35218003 http://dx.doi.org/10.1007/s40262-021-01102-1 |