Residues 140–142, 199–200, 222–223, and 262 in the Surface Glycoprotein of Subgroup A Avian Leukosis Virus Are the Key Sites Determining Tva Receptor Binding Affinity and Infectivity

Subgroup A avian leukosis virus (ALV-A) invades cells through gp85-encoded surface glycoprotein (SU) via specifically recognizing the cellular receptor Tva. To identify the key residues of ALV-A SU that determine the Tva binding affinity and infectivity in DF-1 cells, a strategy of substituting corr...

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Detalles Bibliográficos
Autores principales: Li, Jinqun, Chen, Jian, Dong, Xinyi, Liang, Canxin, Guo, Yanyan, Chen, Xiang, Huang, Mengyu, Liao, Ming, Cao, Weisheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9095613/
https://www.ncbi.nlm.nih.gov/pubmed/35572683
http://dx.doi.org/10.3389/fmicb.2022.868377

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