Cargando…

Cyanidin-3-O-glucoside inhibits the β-catenin/MGMT pathway by upregulating miR-214-5p to reverse chemotherapy resistance in glioma cells

Overcoming resistance to alkylating agents has important clinical significance in glioma. Cyanidin-3-O-glucoside (C3G) has a tumor-suppressive effect on tumor cells. However, whether it plays a role in temozolomide resistance in glioma is still unclear. We constructed a TMZ-resistant LN-18/TR glioma...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhou, Yuan, Chen, Li, Ding, Deping, Li, Ziheng, Cheng, Li, You, Qiuyun, Zhang, Shunbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9095653/
https://www.ncbi.nlm.nih.gov/pubmed/35545654
http://dx.doi.org/10.1038/s41598-022-11757-w