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Cyanidin-3-O-glucoside inhibits the β-catenin/MGMT pathway by upregulating miR-214-5p to reverse chemotherapy resistance in glioma cells
Overcoming resistance to alkylating agents has important clinical significance in glioma. Cyanidin-3-O-glucoside (C3G) has a tumor-suppressive effect on tumor cells. However, whether it plays a role in temozolomide resistance in glioma is still unclear. We constructed a TMZ-resistant LN-18/TR glioma...
Autores principales: | Zhou, Yuan, Chen, Li, Ding, Deping, Li, Ziheng, Cheng, Li, You, Qiuyun, Zhang, Shunbo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9095653/ https://www.ncbi.nlm.nih.gov/pubmed/35545654 http://dx.doi.org/10.1038/s41598-022-11757-w |
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