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Genetic analyses identify pleiotropy and causality for blood proteins and highlight Wnt/β-catenin signalling in migraine
Migraine is a common complex disorder with a significant polygenic SNP heritability ([Formula: see text] ). Here we utilise genome-wide association study (GWAS) summary statistics to study pleiotropy between blood proteins and migraine under the polygenic model. We estimate [Formula: see text] for 4...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9095680/ https://www.ncbi.nlm.nih.gov/pubmed/35546551 http://dx.doi.org/10.1038/s41467-022-30184-z |