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Atomic-scale interactions between quorum sensing autoinducer molecules and the mucoid P. aeruginosa exopolysaccharide matrix

Mucoid Pseudomonas aeruginosa is a prevalent cystic fibrosis (CF) lung coloniser whose chronicity is associated with the formation of cation cross-linked exopolysaccharide (EPS) matrices, which form a biofilm that acts as a diffusion barrier, sequestering cationic and neutral antimicrobials, and mak...

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Detalles Bibliográficos
Autores principales: Hills, Oliver J., Yong, Chin W., Scott, Andrew J., Devine, Deirdre A., Smith, James, Chappell, Helen F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9095684/
https://www.ncbi.nlm.nih.gov/pubmed/35545629
http://dx.doi.org/10.1038/s41598-022-11499-9