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Resveratrol blocks retrotransposition of LINE-1 through PPAR α and sirtuin-6

The retroelement long interspersed element-1 (LINE-1 or L1) comprises about 17% of the human genome. L1 retrotransposition is known to cause genomic instability and related disorders, and resveratrol suppresses this retrotransposition; however, the underlying mechanism is still not elucidated. Recen...

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Detalles Bibliográficos
Autores principales:	Okudaira, Noriyuki, Ishizaka, Yukihito, Tamamori-Adachi, Mimi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9095727/ https://www.ncbi.nlm.nih.gov/pubmed/35546166 http://dx.doi.org/10.1038/s41598-022-11761-0

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