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Septic shock in a woman with a hydatidiform mole: A case report
Hydatidiform moles can be fatal because of the risk of massive bleeding or thyroid storm; however, they rarely occur concomitantly with sepsis. We present herein the case of a woman with a hydatidiform mole with septic shock. A 30-year-old multiparous woman with Basedow's disease presented with...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9095736/ https://www.ncbi.nlm.nih.gov/pubmed/35574176 http://dx.doi.org/10.1016/j.crwh.2022.e00417 |
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author | Yoshimoto, Yuki Murata, Tsuyoshi Machida, Moeko Nozawa, Yoshihiro Nakamura, Soichi Yamauchi, Ryuji |
author_facet | Yoshimoto, Yuki Murata, Tsuyoshi Machida, Moeko Nozawa, Yoshihiro Nakamura, Soichi Yamauchi, Ryuji |
author_sort | Yoshimoto, Yuki |
collection | PubMed |
description | Hydatidiform moles can be fatal because of the risk of massive bleeding or thyroid storm; however, they rarely occur concomitantly with sepsis. We present herein the case of a woman with a hydatidiform mole with septic shock. A 30-year-old multiparous woman with Basedow's disease presented with fever, amenorrhea, and vaginal bleeding. Transvaginal ultrasonography revealed an enlarged uterus with an intrauterine vesicular mass (74.3 × 93.0 mm). Human chorionic gonadotropin level was 994,000 mIU/mL. C-reactive protein was elevated, and blood cultures were positive (gram-negative rods), indicating infection. After administering antibiotics (tazobactam and piperacillin), blood pressure suddenly decreased (69/45 mmHg), requiring stabilization with noradrenaline and albumin. The uterine contents were naturally expelled, followed by dilatation and curettage after her vital signs and general condition gradually improved. The pathological diagnosis was a complete hydatidiform mole. Culture of the intrauterine contents revealed Escherichia coli, leading to the potentially fatal diagnosis of septic shock associated with a hydatidiform mole. |
format | Online Article Text |
id | pubmed-9095736 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-90957362022-05-13 Septic shock in a woman with a hydatidiform mole: A case report Yoshimoto, Yuki Murata, Tsuyoshi Machida, Moeko Nozawa, Yoshihiro Nakamura, Soichi Yamauchi, Ryuji Case Rep Womens Health Article Hydatidiform moles can be fatal because of the risk of massive bleeding or thyroid storm; however, they rarely occur concomitantly with sepsis. We present herein the case of a woman with a hydatidiform mole with septic shock. A 30-year-old multiparous woman with Basedow's disease presented with fever, amenorrhea, and vaginal bleeding. Transvaginal ultrasonography revealed an enlarged uterus with an intrauterine vesicular mass (74.3 × 93.0 mm). Human chorionic gonadotropin level was 994,000 mIU/mL. C-reactive protein was elevated, and blood cultures were positive (gram-negative rods), indicating infection. After administering antibiotics (tazobactam and piperacillin), blood pressure suddenly decreased (69/45 mmHg), requiring stabilization with noradrenaline and albumin. The uterine contents were naturally expelled, followed by dilatation and curettage after her vital signs and general condition gradually improved. The pathological diagnosis was a complete hydatidiform mole. Culture of the intrauterine contents revealed Escherichia coli, leading to the potentially fatal diagnosis of septic shock associated with a hydatidiform mole. Elsevier 2022-04-27 /pmc/articles/PMC9095736/ /pubmed/35574176 http://dx.doi.org/10.1016/j.crwh.2022.e00417 Text en © 2022 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Article Yoshimoto, Yuki Murata, Tsuyoshi Machida, Moeko Nozawa, Yoshihiro Nakamura, Soichi Yamauchi, Ryuji Septic shock in a woman with a hydatidiform mole: A case report |
title | Septic shock in a woman with a hydatidiform mole: A case report |
title_full | Septic shock in a woman with a hydatidiform mole: A case report |
title_fullStr | Septic shock in a woman with a hydatidiform mole: A case report |
title_full_unstemmed | Septic shock in a woman with a hydatidiform mole: A case report |
title_short | Septic shock in a woman with a hydatidiform mole: A case report |
title_sort | septic shock in a woman with a hydatidiform mole: a case report |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9095736/ https://www.ncbi.nlm.nih.gov/pubmed/35574176 http://dx.doi.org/10.1016/j.crwh.2022.e00417 |
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