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Synergistic effect of IFN-γ and IL-1β on PD-L1 expression in hepatocellular carcinoma
Immunotherapy using anti-programmed death 1 ligand 1 (PD-L1) antibodies has shown clinical efficacy against hepatocellular carcinoma (HCC) and is recognized as the first-line treatment for unresectable HCC. PD-L1 expression is affected by various cytokines produced by immune cells in the tumor micro...
Autores principales: | Numata, Yasunao, Akutsu, Noriyuki, Ishigami, Keisuke, Koide, Hideyuki, Wagatsuma, Kohei, Motoya, Masayo, Sasaki, Shigeru, Nakase, Hiroshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9095738/ https://www.ncbi.nlm.nih.gov/pubmed/35573813 http://dx.doi.org/10.1016/j.bbrep.2022.101270 |
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