Bioavailability and Safety of a New Highly Concentrated Midazolam Nasal Spray Compared to Buccal and Intravenous Midazolam Treatment in Chinese Healthy Volunteers

INTRODUCTION: Buccal midazolam treatment is licensed in the European Union for prolonged acute convulsive seizures in children and adolescents, but the buccal pathway is often hampered by jaw clenching, hypersalivation, or uncontrolled swallowing. Midazolam formulations that are more secure, reliabl...

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Detalles Bibliográficos
Autores principales: Wang, Hui, Huang, Jie, Yang, Shuang, Zhang, Xing-fei, Yang, Xiaoyan, Cui, Chang, Zou, Chan, Li, Li-e, Zhang, Min, Mao, Miao-fu, Zhou, Xiang, Duan, Kai-ming, Wang, Sai-ying, Yang, Guo-ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Healthcare 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9095771/
https://www.ncbi.nlm.nih.gov/pubmed/35129802
http://dx.doi.org/10.1007/s40120-022-00329-9

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