Spinning sugars in antigen biosynthesis: characterization of the Coxiella burnetii and Streptomyces griseus TDP-sugar epimerases

The sugars streptose and dihydrohydroxystreptose (DHHS) are unique to the bacteria Streptomyces griseus and Coxiella burnetii, respectively. Streptose forms the central moiety of the antibiotic streptomycin, while DHHS is found in the O-antigen of the zoonotic pathogen C. burnetii. Biosynthesis of t...

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Detalles Bibliográficos
Autores principales: Cross, Alice R., Roy, Sumita, Vivoli Vega, Mirella, Rejzek, Martin, Nepogodiev, Sergey A., Cliff, Matthew, Salmon, Debbie, Isupov, Michail N., Field, Robert A., Prior, Joann L., Harmer, Nicholas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9095892/
https://www.ncbi.nlm.nih.gov/pubmed/35398092
http://dx.doi.org/10.1016/j.jbc.2022.101903

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