Cargando…

Polymyxin B-Associated Nephrotoxicity and Its Predictors: A Retrospective Study in Carbapenem-Resistant Gram-Negative Bacterial Infections

Polymyxin B (PMB), a kind of polymyxin, was widely used in carbapenem-resistant Gram-negative bacterial (CR-GNB) infections. However, adverse reactions such as nephrotoxicity and neurotoxicity limit its use in clinical practice. The aim of this study was to explore PMB associated with nephrotoxicity...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wu, Xiao-Li, Long, Wen-Ming, Lu, Qiong, Teng, Xin-Qi, Qi, Ting-Ting, Qu, Qiang, He, Ge-Fei, Qu, Jian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9096016/ https://www.ncbi.nlm.nih.gov/pubmed/35571125 http://dx.doi.org/10.3389/fphar.2022.672543

Ejemplares similares

Effectiveness and Nephrotoxicity of Intravenous Polymyxin B in Carbapenem-Resistant Gram-Negative Bacterial Infections Among Chinese Children
por: Jia, Xuedong, et al.
Publicado: (2022)

A Comparative Study of the Microbiological Efficacy of Polymyxin B on Different Carbapenem-Resistant Gram-Negative Bacteria Infections
por: Lu, Qiong, et al.
Publicado: (2021)

Polymyxin B-Based Regimens for Patients Infected with Carbapenem-Resistant Gram-Negative Bacteria: Clinical and Microbiological Efficacy, Mortality, and Safety
por: Qu, Jian, et al.
Publicado: (2022)

Nephrotoxicity and Efficacy Assessment of Polymyxin B Use in Renal Transplant Patients
por: Wen, Yu-Xin, et al.
Publicado: (2022)

Comparison of the clinical efficacy and toxicity of nebulized polymyxin monotherapy and combined intravenous and nebulized polymyxin for the treatment of ventilator-associated pneumonia caused by carbapenem-resistant gram-negative bacteria: a retrospective cohort study
por: Wu, Zhenping, et al.
Publicado: (2023)

Efficacy and nephrotoxicity of polymyxin B in elderly patients with carbapenem resistant bacterial infection
por: Xia, G. L., et al.
Publicado: (2023)

An area under the concentration–time curve threshold as a predictor of efficacy and nephrotoxicity for individualizing polymyxin B dosing in patients with carbapenem-resistant gram-negative bacteria
por: Yang, Jing, et al.
Publicado: (2022)

Population Pharmacokinetics of Polymyxin B in Obese Patients for Resistant Gram-Negative Infections
por: Wang, Peile, et al.
Publicado: (2021)

Efficacy and safety of polymyxin B in carbapenem-resistant gram-negative organisms infections
por: Xia, G. L., et al.
Publicado: (2021)

Clinical outcomes and safety of polymyxin B in the treatment of carbapenem-resistant Gram-negative bacterial infections: a real-world multicenter study
por: Zhang, Xiaojuan, et al.
Publicado: (2021)

Population Pharmacokinetics and Limited Sampling Strategy for Therapeutic Drug Monitoring of Polymyxin B in Chinese Patients With Multidrug-Resistant Gram-Negative Bacterial Infections
por: Wang, Peile, et al.
Publicado: (2020)

Clinical Efficacy of Polymyxin B in Patients Infected with Carbapenem-Resistant Organisms
por: Lu, Qiong, et al.
Publicado: (2021)

Treatment of Carbapenem-Resistant Multidrug-Resistant Gram-Negative Bacilli with Intracerebroventricular Injection of Polymyxin B: A Retrospective Study
por: Liu, Dongsheng, et al.
Publicado: (2022)

Effectiveness and Nephrotoxicity of Intravenous Polymyxin B in Chinese Patients With MDR and XDR Nosocomial Pneumonia
por: Zeng, Huihui, et al.
Publicado: (2021)

Pharmacokinetic/Pharmacodynamic Based Breakpoints of Polymyxin B for Bloodstream Infections Caused by Multidrug-Resistant Gram-Negative Pathogens
por: Bian, Xingchen, et al.
Publicado: (2022)

Clinical Experience with High-Dose Polymyxin B against Carbapenem-Resistant Gram-Negative Bacterial Infections—A Cohort Study
por: Cai, Yiying, et al.
Publicado: (2020)

Clinical efficacy and nephrotoxicity of intravenous colistin sulfate in the treatment of carbapenem-resistant gram-negative bacterial infections: a retrospective cohort study
por: Jin, Jun, et al.
Publicado: (2022)

Therapeutic Drug Monitoring of Ceftazidime-Avibactam Concentrations in Carbapenem-Resistant K. pneumoniae-Infected Patients With Different Kidney Statuses
por: Teng, Xin-Qi, et al.
Publicado: (2022)

Ceftazidime-Avibactam Therapy Versus Ceftazidime-Avibactam-Based Combination Therapy in Patients With Carbapenem-Resistant Gram-Negative Pathogens: A Meta-Analysis
por: Li, Dan, et al.
Publicado: (2021)

Pharmacokinetics/pharmacodynamics of polymyxin B in patients with bloodstream infection caused by carbapenem-resistant Klebsiella pneumoniae
por: Yu, Zhenwei, et al.
Publicado: (2022)

Novel Polymyxin Combination With Antineoplastic Mitotane Improved the Bacterial Killing Against Polymyxin-Resistant Multidrug-Resistant Gram-Negative Pathogens
por: Tran, Thien B., et al.
Publicado: (2018)

Treatment Options for Carbapenem-resistant Gram-negative Bacterial Infections
por: Doi, Yohei
Publicado: (2019)

Activities of Cefiderocol with Simulated Human Plasma Concentrations against Carbapenem-Resistant Gram-Negative Bacilli in an In Vitro Chemostat Model
por: Matsumoto, Shuhei, et al.
Publicado: (2020)

Coarse-grained simulations uncover Gram-negative bacterial defense against polymyxins by the outer membrane
por: Jiang, Xukai, et al.
Publicado: (2021)

2542. Attenuation of Polymyxin and Aminoglycoside-Associated Nephrotoxicity
por: Hudson, Cole, et al.
Publicado: (2023)

The Difference Between Polymyxin B and Polymyxin E in Causing Skin Hyerpigmentation
por: Zou, Dongna, et al.
Publicado: (2021)

Antimicrobial Peptides for Gram-Negative Sepsis: A Case for the Polymyxins
por: David, Sunil A.
Publicado: (2012)

Probing the Penetration of Antimicrobial Polymyxin Lipopeptides into Gram-Negative Bacteria
por: Deris, Zakuan Z., et al.
Publicado: (2014)

Low-dose polymyxin: an option for therapy of Gram-negative sepsis
por: Harm, Stephan, et al.
Publicado: (2016)

Optimizing Polymyxin Combinations Against Resistant Gram-Negative Bacteria
por: Bergen, Phillip J., et al.
Publicado: (2015)

Polymyxin Derivatives that Sensitize Gram-Negative Bacteria to Other Antibiotics
por: Vaara, Martti
Publicado: (2019)

Efficacy of Ceftazidime-Avibactam Versus Polymyxin B and Risk Factors Affecting Clinical Outcomes in Patients With Carbapenem-Resistant Klebsiella pneumoniae Infections a Retrospective Study
por: Fang, Jie, et al.
Publicado: (2021)

Efficacy of Cefiderocol against Carbapenem-Resistant Gram-Negative Bacilli in Immunocompetent-Rat Respiratory Tract Infection Models Recreating Human Plasma Pharmacokinetics
por: Matsumoto, Shuhei, et al.
Publicado: (2017)

Predictors of Mortality in Patients with Infections Due to Carbapenem-Resistant Gram-Negative Bacteria
por: Rivera-Villegas, Hector Orlando, et al.
Publicado: (2023)

Polymyxin B Nephrotoxicity: From Organ to Cell Damage
por: Vattimo, Maria de Fátima Fernandes, et al.
Publicado: (2016)

Curcumin Supplementation Alleviates Polymyxin E-Induced Nephrotoxicity
por: Vazin, Afsaneh, et al.
Publicado: (2020)

Evaluation of the Clinical Systems for Polymyxin Susceptibility Testing of Clinical Gram-Negative Bacteria in China
por: Zhu, Ying, et al.
Publicado: (2021)

Bi-Functional Alginate Oligosaccharide–Polymyxin Conjugates for Improved Treatment of Multidrug-Resistant Gram-Negative Bacterial Infections
por: Stokniene, Joana, et al.
Publicado: (2020)

Crude Mortality Associated With the Empirical Use of Polymyxins in Septic Patients in a Setting of High Prevalence of Carbapenem-Resistant Gram-negative Bacteria: Retrospective Analysis of a Cohort
por: Bezerra, Camila L P A M, et al.
Publicado: (2023)

A retrospective observational study of the treatment with polymyxin B for liver transplantation recipients infected by multidrug‐resistant gram‐negative bacteria
por: Yu, Ling‐Ling, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_9skh019m8f7snt4gulp18kq1s4