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Case Report: Severe Anemia Associated With an Abomasal Fibrosarcoma in a Goat
A 10-year-old female goat was presented to the clinic with lethargy, emaciation, and pale mucous membranes. Laboratory diagnosis revealed severe anemia with regenerative character as well as melena. Blood transfusions were administered, but the animal's condition continued to deteriorate, so it...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9096240/ https://www.ncbi.nlm.nih.gov/pubmed/35573404 http://dx.doi.org/10.3389/fvets.2022.869017 |
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author | Wagener, Matthias Gerhard Beythien, Georg Sterneberg, Markus Polifka, Antje Großmann, Thekla Baumgärtner, Wolfgang Ganter, Martin |
author_facet | Wagener, Matthias Gerhard Beythien, Georg Sterneberg, Markus Polifka, Antje Großmann, Thekla Baumgärtner, Wolfgang Ganter, Martin |
author_sort | Wagener, Matthias Gerhard |
collection | PubMed |
description | A 10-year-old female goat was presented to the clinic with lethargy, emaciation, and pale mucous membranes. Laboratory diagnosis revealed severe anemia with regenerative character as well as melena. Blood transfusions were administered, but the animal's condition continued to deteriorate, so it was euthanized. The main finding in the necropsy was an abomasal neoplasia with two metastases in the mesenterium which was positive for vimentin, but negative for smooth muscle actin and c-kit using immunohistochemistry, indicating a fibrosarcoma that might have contributed to gastrointestinal blood loss. Further pathological findings consisted of changes in the liver cells as well as a cervical leiomyoma. These findings illustrate that intestinal blood loss due to neoplasia should also be considered in older goats with anemia. |
format | Online Article Text |
id | pubmed-9096240 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-90962402022-05-13 Case Report: Severe Anemia Associated With an Abomasal Fibrosarcoma in a Goat Wagener, Matthias Gerhard Beythien, Georg Sterneberg, Markus Polifka, Antje Großmann, Thekla Baumgärtner, Wolfgang Ganter, Martin Front Vet Sci Veterinary Science A 10-year-old female goat was presented to the clinic with lethargy, emaciation, and pale mucous membranes. Laboratory diagnosis revealed severe anemia with regenerative character as well as melena. Blood transfusions were administered, but the animal's condition continued to deteriorate, so it was euthanized. The main finding in the necropsy was an abomasal neoplasia with two metastases in the mesenterium which was positive for vimentin, but negative for smooth muscle actin and c-kit using immunohistochemistry, indicating a fibrosarcoma that might have contributed to gastrointestinal blood loss. Further pathological findings consisted of changes in the liver cells as well as a cervical leiomyoma. These findings illustrate that intestinal blood loss due to neoplasia should also be considered in older goats with anemia. Frontiers Media S.A. 2022-04-28 /pmc/articles/PMC9096240/ /pubmed/35573404 http://dx.doi.org/10.3389/fvets.2022.869017 Text en Copyright © 2022 Wagener, Beythien, Sterneberg, Polifka, Großmann, Baumgärtner and Ganter. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Veterinary Science Wagener, Matthias Gerhard Beythien, Georg Sterneberg, Markus Polifka, Antje Großmann, Thekla Baumgärtner, Wolfgang Ganter, Martin Case Report: Severe Anemia Associated With an Abomasal Fibrosarcoma in a Goat |
title | Case Report: Severe Anemia Associated With an Abomasal Fibrosarcoma in a Goat |
title_full | Case Report: Severe Anemia Associated With an Abomasal Fibrosarcoma in a Goat |
title_fullStr | Case Report: Severe Anemia Associated With an Abomasal Fibrosarcoma in a Goat |
title_full_unstemmed | Case Report: Severe Anemia Associated With an Abomasal Fibrosarcoma in a Goat |
title_short | Case Report: Severe Anemia Associated With an Abomasal Fibrosarcoma in a Goat |
title_sort | case report: severe anemia associated with an abomasal fibrosarcoma in a goat |
topic | Veterinary Science |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9096240/ https://www.ncbi.nlm.nih.gov/pubmed/35573404 http://dx.doi.org/10.3389/fvets.2022.869017 |
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