Cargando…

Long non-coding RNA MEG3 regulates the progress of osteoarthritis by regulating the miR-34a/Klotho axis

BACKGROUND: Osteoarthritis (OA) is one of the most common chronic diseases today, and its prevalence and incidence are expected to increase as life expectancy increases. By investigating the inhibition of long non-coding RNA maternally expressed gene 3 (lncRNA MEG3) in OA, we hope to provide some ne...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xiong, Gaoxin, Wang, Shuangli, Pan, Zhengjun, Liu, Ning, Zhao, Donglei, Zha, Zhengang, Ning, Rende
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AME Publishing Company 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9096400/ https://www.ncbi.nlm.nih.gov/pubmed/35571440 http://dx.doi.org/10.21037/atm-22-894

Ejemplares similares

Bcl‐xL expression following articular cartilage injury and its effects on the biological function of chondrocytes
por: Pan, Zhengjun, et al.
Publicado: (2020)

MEG3 Regulates CSE-Induced Apoptosis by Regulating miR-421/DFFB Signal Axis
por: Bi, Hui, et al.
Publicado: (2023)

Inhibition of microRNA-21 decreases the invasiveness of fibroblast-like synoviocytes in rheumatoid arthritis via TGF(β)/Smads signaling pathway
por: Xiong, Gaoxin, et al.
Publicado: (2016)

MicroRNA-9 regulates the development of knee osteoarthritis through the NF-kappaB1 pathway in chondrocytes
por: Gu, Ronghe, et al.
Publicado: (2016)

Bax Targeted by miR-29a Regulates Chondrocyte Apoptosis in Osteoarthritis
por: Miao, Guiqiang, et al.
Publicado: (2019)

The lncRNA MEG3 downregulation leads to osteoarthritis progression via miR-16/SMAD7 axis
por: Xu, Jin, et al.
Publicado: (2017)

MEG3 promotes proliferation and inhibits apoptosis in osteoarthritis chondrocytes by miR-361-5p/FOXO1 axis
por: Wang, Anying, et al.
Publicado: (2019)

Long non-coding RNA MEG3 promotes fibrosis and inflammatory response in diabetic nephropathy via miR-181a/Egr-1/TLR4 axis
por: Zha, Fangfang, et al.
Publicado: (2019)

Tumor-Suppressive Function of lncRNA-MEG3 in Glioma Cells by Regulating miR-6088/SMARCB1 Axis
por: Gong, Xin, et al.
Publicado: (2020)

LncRNA MEG3 promotes cisplatin sensitivity of cervical cancer cells by regulating the miR-21/PTEN axis
por: Du, Ying, et al.
Publicado: (2022)

GPR120 is an important inflammatory regulator in the development of osteoarthritis
por: Chen, Yuanfeng, et al.
Publicado: (2018)

The Long Non-coding RNA MEG3/miR-let-7c-5p Axis Regulates Ethanol-Induced Hepatic Steatosis and Apoptosis by Targeting NLRC5
por: Wang, Qin, et al.
Publicado: (2018)

lncRNA MEG8 is downregulated in osteoarthritis and regulates chondrocyte cell proliferation, apoptosis and inflammation
por: Xie, Wei, et al.
Publicado: (2021)

Long non-coding RNA MEG3 inhibits cell migration and invasion of non-small cell lung cancer cells by regulating the miR-21-5p/PTEN axis
por: Lv, Dongjin, et al.
Publicado: (2021)

Circ0083429 Regulates Osteoarthritis Progression via the Mir-346/SMAD3 Axis
por: Yao, Teng, et al.
Publicado: (2021)

miR-34a Regulates Sperm Motility in Zebrafish
por: Guo, Wenjie, et al.
Publicado: (2017)

Klotho negatively regulated aerobic glycolysis in colorectal cancer via ERK/HIF1α axis
por: Li, Qingguo, et al.
Publicado: (2018)

Feto-maternal cholesterol transport regulated by β-Klotho–FGF15 axis is essential for fetal growth
por: Kobayashi, Kanako, et al.
Publicado: (2023)

Understanding the Stony Bridge between Osteoporosis and Vascular Calcification: Impact of the FGF23/Klotho axis
por: Wei, Xu, et al.
Publicado: (2021)

Long Non-Coding RNA MEG8 Suppresses Hypoxia-Induced Excessive Proliferation, Migration and Inflammation of Vascular Smooth Muscle Cells by Regulation of the miR-195-5p/RECK Axis
por: Xu, Dexing, et al.
Publicado: (2021)

Klotho as Potential Autophagy Regulator and Therapeutic Target
por: Zhou, Hongjing, et al.
Publicado: (2021)

The miR-34a-LDHA axis regulates glucose metabolism and tumor growth in breast cancer
por: Xiao, Xiangsheng, et al.
Publicado: (2016)

miR-122/SIRT1 axis regulates chondrocyte extracellular matrix degradation in osteoarthritis
por: Bai, Yinwei, et al.
Publicado: (2020)

The novel circ_0028171/miR-218-5p/IKBKB axis promotes osteosarcoma cancer progression
por: Pan, Feng, et al.
Publicado: (2020)

The fibroblast growth factor–Klotho axis at molecular level
por: Sun, Fuqiang, et al.
Publicado: (2023)

Long Non-Coding RNA LINC00662 Regulated Proliferation and Migration by Targeting miR-34a-5p/LMAN2L Axis in Glioma
por: Geng, Yibo, et al.
Publicado: (2020)

miR-34a regulates adipogenesis in porcine intramuscular adipocytes by targeting ACSL4
por: Wang, Wenwen, et al.
Publicado: (2020)

Long non-coding RNA MEG3 regulates autophagy after cerebral ischemia/reperfusion injury
por: Li, Tian-Hao, et al.
Publicado: (2021)

Quantitative Proteomic Analysis of Gene Regulation by miR-34a and miR-34c
por: Ebner, Olivia A., et al.
Publicado: (2014)

Skeletal muscle as a regulator of the longevity protein, Klotho
por: Avin, Keith G., et al.
Publicado: (2014)

Regulation of S-formylglutathione hydrolase by the anti-aging gene klotho
por: Xu, Yuechi, et al.
Publicado: (2017)

Exercise intensity regulates cytokine and klotho responses in men
por: Middelbeek, Roeland J. W., et al.
Publicado: (2021)

Down-regulation of long non-coding RNA MEG3 suppresses osteogenic differentiation of periodontal ligament stem cells (PDLSCs) through miR-27a-3p/IGF1 axis in periodontitis
por: Liu, Yi, et al.
Publicado: (2019)

LncRNA PVT1 regulates biological function of osteoarthritis cells by regulating miR-497/AKT3 axis
por: Xu, Jinming, et al.
Publicado: (2022)

Depletion of lncRNA MEG3 Ameliorates Imatinib-Induced Injury of Cardiomyocytes via Regulating miR-129-5p/HMGB1 Axis
por: Tang, Peng, et al.
Publicado: (2023)

Long non-coding RNA MEG3 suppresses the growth of glioma cells by regulating the miR-96-5p/MTSS1 signaling pathway
por: Zhang, Shoudan, et al.
Publicado: (2019)

lncRNA MEG3 Suppresses the Progression of Ankylosis Spondylitis by Regulating the Let-7i/SOST Axis
por: Ma, Junjie, et al.
Publicado: (2020)

Long non-coding RNA MEG3 is involved in osteogenic differentiation and bone diseases (Review)
por: Sun, Hong, et al.
Publicado: (2020)

Role of metformin in functional endometrial hyperplasia and polycystic ovary syndrome involves the regulation of MEG3/miR-223/GLUT4 and SNHG20/miR-4486/GLUT4 signaling
por: Liu, Jie, et al.
Publicado: (2022)

Up-regulated miR-199a-5p in gastric cancer functions as an oncogene and targets klotho
por: He, Xu-Jun, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_c78bqtogvi2og23kvoqun895lb