Oncostatin M promotes the ox-LDL-induced activation of NLRP3 inflammasomes via the NF-κB pathway in THP-1 macrophages and promotes the progression of atherosclerosis

BACKGROUND: Oncostatin M (OSM) is reported to be involved in many stages of atherosclerosis, including endothelial dysfunction, chronic inflammation, and smooth muscle cell migration. This study explored the effects of OSM on foam cell formation and its corresponding molecular mechanisms. METHODS: T...

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Detalles Bibliográficos
Autores principales: Liu, Cheng, Wu, Jiang, Jia, Haiyun, Lu, Caixia, Liu, Junjun, Li, Yongxin, Guo, Mingjin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9096425/
https://www.ncbi.nlm.nih.gov/pubmed/35571419
http://dx.doi.org/10.21037/atm-22-560

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