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Inhibition of MEK-ERK pathway enhances oncolytic vaccinia virus replication in doxorubicin-resistant ovarian cancer

Oncolytic vaccinia virus (OVV) has been reported to induce cell death in various types of cancer; however, the oncolytic activity of OVV in drug-resistant ovarian cancer remains limited. In the present study, we established doxorubicin-resistant ovarian cancer cells (A2780-R) from the A2780 human ov...

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Detalles Bibliográficos
Autores principales: Lee, Seoyul, Yang, Wookyeom, Kim, Dae Kyoung, Kim, Hojun, Shin, Minjoo, Choi, Kyung Un, Suh, Dong Soo, Kim, Yun Hak, Hwang, Tae-Ho, Kim, Jae Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9096472/
https://www.ncbi.nlm.nih.gov/pubmed/35592390
http://dx.doi.org/10.1016/j.omto.2022.04.006