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Enhancement and mapping of tolerance to salt stress and 5-fluorocytosine in synthetic yeast strains via SCRaMbLE
Varied environmental stress can affect cell growth and activity of the cellular catalyst. Traditional path of adaptive evolution generally takes a long time to achieve a tolerance phenotype, meanwhile, it is a challenge to dissect the underlying genetic mechanism. Here, using SCRaMbLE, a genome scal...
Autores principales: | Kang, Jianping, Li, Jieyi, Guo, Zhou, Zhou, Sijie, Su, Shuxin, Xiao, Wenhai, Wu, Yi, Yuan, Yingjin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
KeAi Publishing
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9096473/ https://www.ncbi.nlm.nih.gov/pubmed/35601823 http://dx.doi.org/10.1016/j.synbio.2022.04.003 |
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