Cargando…

Cohort profile: The Xinjiang Multiethnic Cohort (XMC) study

PURPOSE: To investigate the potential causal link between heredity, geographical environment, diet and other lifestyle factors with long-term health consequences, we established the Xinjiang Multiethnic Cohort Study (XMC), the first large-scale prospective cohort in Xinjiang, China. PARTICIPANTS: XM...

Descripción completa

Detalles Bibliográficos
Autores principales: Tao, Luo, Tian, Tian, Liu, Lirong, Zhang, Zewen, Sun, Qi, Sun, Gaofeng, Dai, Jianghong, Yan, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9096539/
https://www.ncbi.nlm.nih.gov/pubmed/35545396
http://dx.doi.org/10.1136/bmjopen-2020-048242
_version_ 1784705998670266368
author Tao, Luo
Tian, Tian
Liu, Lirong
Zhang, Zewen
Sun, Qi
Sun, Gaofeng
Dai, Jianghong
Yan, Hong
author_facet Tao, Luo
Tian, Tian
Liu, Lirong
Zhang, Zewen
Sun, Qi
Sun, Gaofeng
Dai, Jianghong
Yan, Hong
author_sort Tao, Luo
collection PubMed
description PURPOSE: To investigate the potential causal link between heredity, geographical environment, diet and other lifestyle factors with long-term health consequences, we established the Xinjiang Multiethnic Cohort Study (XMC), the first large-scale prospective cohort in Xinjiang, China. PARTICIPANTS: XMC commenced in 2018 and enrolled participants from three study sites (Urumqi, Hotan and Ili) in Xinjiang, China. Data collected include standard baseline questionnaire, physical measurement, biological specimen. In addition, about one-third of participants were assessed habitual diet by a more detailed semiquantitative food frequency questionnaire which included 127 foods items at baseline FINDINGS TO DATE: Finally, a total of 30 949 participants, with 32.37% from Urumqi, 41.75% from Hotan, and 25.88% from Ili were recruited in XMC. The average age of participants was 56.21 years for men, and 54.75 years for women. More than 60% of participants in all three survey sites reported an average consumption of fruit and vegetable three or more times per week. In Hotan and Ili, the staple food was wheaten food, whereas, in Urumqi, rice and wheaten food was the food staples. Consumption of white meat, such as fish and poultry, was lower in the three survey locations. Based on self-reported disease from study participants, the five most common chronic diseases among participants across all three survey locations were dyslipidaemia, hypertension, cholecystitis, diabetes, ischaemic heart disease. FUTURE PLANS: First, we will collect all health-related records of the study participants in January each year for the previous year. Second, 10% of subjects were randomly selected for telephone follow-up in the final year of cohort building. Finally, as planned, we will revisit the study subjects on site every 2–3 years. Again, we will conduct face-to-face questionnaires and collect biological specimens such as blood and urine from the study subjects.
format Online
Article
Text
id pubmed-9096539
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher BMJ Publishing Group
record_format MEDLINE/PubMed
spelling pubmed-90965392022-05-18 Cohort profile: The Xinjiang Multiethnic Cohort (XMC) study Tao, Luo Tian, Tian Liu, Lirong Zhang, Zewen Sun, Qi Sun, Gaofeng Dai, Jianghong Yan, Hong BMJ Open Epidemiology PURPOSE: To investigate the potential causal link between heredity, geographical environment, diet and other lifestyle factors with long-term health consequences, we established the Xinjiang Multiethnic Cohort Study (XMC), the first large-scale prospective cohort in Xinjiang, China. PARTICIPANTS: XMC commenced in 2018 and enrolled participants from three study sites (Urumqi, Hotan and Ili) in Xinjiang, China. Data collected include standard baseline questionnaire, physical measurement, biological specimen. In addition, about one-third of participants were assessed habitual diet by a more detailed semiquantitative food frequency questionnaire which included 127 foods items at baseline FINDINGS TO DATE: Finally, a total of 30 949 participants, with 32.37% from Urumqi, 41.75% from Hotan, and 25.88% from Ili were recruited in XMC. The average age of participants was 56.21 years for men, and 54.75 years for women. More than 60% of participants in all three survey sites reported an average consumption of fruit and vegetable three or more times per week. In Hotan and Ili, the staple food was wheaten food, whereas, in Urumqi, rice and wheaten food was the food staples. Consumption of white meat, such as fish and poultry, was lower in the three survey locations. Based on self-reported disease from study participants, the five most common chronic diseases among participants across all three survey locations were dyslipidaemia, hypertension, cholecystitis, diabetes, ischaemic heart disease. FUTURE PLANS: First, we will collect all health-related records of the study participants in January each year for the previous year. Second, 10% of subjects were randomly selected for telephone follow-up in the final year of cohort building. Finally, as planned, we will revisit the study subjects on site every 2–3 years. Again, we will conduct face-to-face questionnaires and collect biological specimens such as blood and urine from the study subjects. BMJ Publishing Group 2022-05-10 /pmc/articles/PMC9096539/ /pubmed/35545396 http://dx.doi.org/10.1136/bmjopen-2020-048242 Text en © Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) .
spellingShingle Epidemiology
Tao, Luo
Tian, Tian
Liu, Lirong
Zhang, Zewen
Sun, Qi
Sun, Gaofeng
Dai, Jianghong
Yan, Hong
Cohort profile: The Xinjiang Multiethnic Cohort (XMC) study
title Cohort profile: The Xinjiang Multiethnic Cohort (XMC) study
title_full Cohort profile: The Xinjiang Multiethnic Cohort (XMC) study
title_fullStr Cohort profile: The Xinjiang Multiethnic Cohort (XMC) study
title_full_unstemmed Cohort profile: The Xinjiang Multiethnic Cohort (XMC) study
title_short Cohort profile: The Xinjiang Multiethnic Cohort (XMC) study
title_sort cohort profile: the xinjiang multiethnic cohort (xmc) study
topic Epidemiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9096539/
https://www.ncbi.nlm.nih.gov/pubmed/35545396
http://dx.doi.org/10.1136/bmjopen-2020-048242
work_keys_str_mv AT taoluo cohortprofilethexinjiangmultiethniccohortxmcstudy
AT tiantian cohortprofilethexinjiangmultiethniccohortxmcstudy
AT liulirong cohortprofilethexinjiangmultiethniccohortxmcstudy
AT zhangzewen cohortprofilethexinjiangmultiethniccohortxmcstudy
AT sunqi cohortprofilethexinjiangmultiethniccohortxmcstudy
AT sungaofeng cohortprofilethexinjiangmultiethniccohortxmcstudy
AT daijianghong cohortprofilethexinjiangmultiethniccohortxmcstudy
AT yanhong cohortprofilethexinjiangmultiethniccohortxmcstudy