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Comparison of Bayesian vs Frequentist Adaptive Trial Design in the Stroke Hyperglycemia Insulin Network Effort Trial

IMPORTANCE: Bayesian adaptive trial design has the potential to create more efficient clinical trials. However, a barrier to the uptake of bayesian adaptive designs for confirmatory trials is limited experience with how they may perform compared with a frequentist design. OBJECTIVE: To compare the p...

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Detalles Bibliográficos
Autores principales:	Broglio, Kristine, Meurer, William J., Durkalski, Valerie, Pauls, Qi, Connor, Jason, Berry, Donald, Lewis, Roger J., Johnston, Karen C., Barsan, William G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Medical Association 2022
Materias:	Original Investigation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9096598/ https://www.ncbi.nlm.nih.gov/pubmed/35544137 http://dx.doi.org/10.1001/jamanetworkopen.2022.11616

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