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Co-Crystal of Rosiglitazone With Berberine Ameliorates Hyperglycemia and Insulin Resistance Through the PI3K/AKT/TXNIP Pathway In Vivo and In Vitro

Background: Type 2 diabetes mellitus (T2DM) is a chronic metabolic disease characterized by insulin resistance and hyperglycemia. This study examined the effect and elucidated the mechanism of improvement of hyperglycemia and insulin resistance by a co-crystal of rosiglitazone with berberine (RB) in...

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Detalles Bibliográficos
Autores principales:	He, Qichen, Chen, Bo, Wang, Gang, Zhou, Duanfang, Zeng, Hongfang, Li, Xiaoli, Song, Yi, Yu, Xiaoping, Liang, Wenxin, Chen, Huiling, Liu, Xu, Wu, Qiuya, Wu, Lihong, Zhang, Limei, Li, Huizhen, Hu, Xiangnan, Zhou, Weiying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9096649/ https://www.ncbi.nlm.nih.gov/pubmed/35571083 http://dx.doi.org/10.3389/fphar.2022.842879

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