Copy Number Variant Risk Scores Associated With Cognition, Psychopathology, and Brain Structure in Youths in the Philadelphia Neurodevelopmental Cohort

IMPORTANCE: Psychiatric and cognitive phenotypes have been associated with a range of specific, rare copy number variants (CNVs). Moreover, IQ is strongly associated with CNV risk scores that model the predicted risk of CNVs across the genome. But the utility of CNV risk scores for psychiatric pheno...

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Detalles Bibliográficos
Autores principales: Alexander-Bloch, Aaron, Huguet, Guillaume, Schultz, Laura M., Huffnagle, Nicholas, Jacquemont, Sebastien, Seidlitz, Jakob, Saci, Zohra, Moore, Tyler M., Bethlehem, Richard A. I., Mollon, Josephine, Knowles, Emma K., Raznahan, Armin, Merikangas, Alison, Chaiyachati, Barbara H., Raman, Harshini, Schmitt, J. Eric, Barzilay, Ran, Calkins, Monica E., Shinohara, Russel T., Satterthwaite, Theodore D., Gur, Ruben C., Glahn, David C., Almasy, Laura, Gur, Raquel E., Hakonarson, Hakon, Glessner, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Medical Association 2022
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9096695/
https://www.ncbi.nlm.nih.gov/pubmed/35544191
http://dx.doi.org/10.1001/jamapsychiatry.2022.1017

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