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Genetic Alteration Analysis of IDH1, IDH2, CDKN2A, MYB and MYBL1 in Pediatric Low-Grade Gliomas

OBJECTIVE: To investigate pediatric low-grade gliomas for alterations in IDH1, IDH2, CDKN2A, MYB, and MYBL1. MATERIALS AND METHODS: DNA and RNA were extracted from 62 pediatric gliomas. Molecular methods included PCR, RT-PCR, and RNA sequencing; Sanger sequencing was used for validation. RESULTS: An...

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Detalles Bibliográficos
Autores principales:	Barinfeld, Orit, Zahavi, Alon, Weiss, Shirel, Toledano, Helen, Michowiz, Shalom, Goldenberg-Cohen, Nitza
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Surgery
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9096721/ https://www.ncbi.nlm.nih.gov/pubmed/35574540 http://dx.doi.org/10.3389/fsurg.2022.880048

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